SCHEMBL11921766

SCHEMBL11921766

Cc1ccc(CC(NC(=O)CCCCCOC(=O)c2ccc(N=C=O)cc2)C(=O)OCCCCCC(=O)Oc2ccc(N=C=O)cc2)cc1OC#N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.35
▸ SLC22A2 O15244 1/20 0.35
▸ TMPRSS2 O15393 1/20 0.35
▸ F2 P00734 1/20 0.35
▸ F10 P00742 1/20 0.35
▸ PLG P00747 1/20 0.35
▸ F12 P00748 1/20 0.35
▸ PLAU P00749 1/20 0.35
▸ PLAT P00750 1/20 0.35
▸ KLKB1 P03952 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ HPN P05981 1/20 0.35
▸ CHRM2 P08172 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ SLC6A2 P23975 1/20 0.35
▸ SLC6A3 Q01959 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ KCNH2 Q12809 1/20 0.35
▸ SLC47A2 Q86VL8 1/20 0.35
▸ SLC47A1 Q96FL8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15258095 0.97 CYP1A2 (0.35) MEN1SLC22A2TMPRSS2F2F10
SCHEMBL11921753 0.90 PRSS1 (0.38) MEN1SLC22A2TMPRSS2F2F10
SCHEMBL16270610 0.89 MEN1 (0.38) MEN1SLC22A2TMPRSS2F2F10
SCHEMBL11925962 0.88 HDAC1 (0.40) MEN1SLC22A2TMPRSS2F2F10
SCHEMBL11921765 0.86 MAPT (0.32) PRSS1PRSS2PRSS3MAPT
SCHEMBL15259407 0.86 CYP1A2 (0.37) MEN1SLC22A2TMPRSS2F2F10
SCHEMBL11921764 0.85 TYR (0.36) PRSS1PRSS2PRSS3MAPT
SCHEMBL20040326 0.79 MEN1 (0.36) MEN1SLC22A2TMPRSS2F2F10
SCHEMBL11921789 0.78 NPC1 (0.41) MEN1SLC22A2TMPRSS2F2F10
SCHEMBL11921791 0.77 CTSL (0.34) PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-07-12 — — US disclosed
US-9868696-B2 Amino acid derivatives and absorbable polymers therefrom Bezwada Biomedial, LLC (US) 2018-01-16 — — US disclosed
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2016-09-08 — — US disclosed
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-06-25 — — US disclosed
US-9012677-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2015-04-21 — — US disclosed
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-03-05 — — US disclosed
US-8901341-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-12-02 — — US disclosed
US-8461372-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC 2013-06-11 — — US disclosed
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2012-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM SLC7A1, SLC3A2, BCAT2 MEN1 4109/4885SLC22A2 454/4885TMPRSS2 616/4885
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 MEN1 4211/4885SLC22A2 725/4885TMPRSS2 529/4885
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 MEN1 4211/4885SLC22A2 725/4885TMPRSS2 529/4885
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 MEN1 4211/4885SLC22A2 725/4885TMPRSS2 529/4885
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 MEN1 4211/4885SLC22A2 725/4885TMPRSS2 529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback