SCHEMBL11921747

SCHEMBL11921747

N#COc1ccc(CC(NC(=O)COC(=O)c2ccc(N=C=O)cc2)C(=O)OCC(=O)Oc2ccc(N=C=O)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PRSS1 P07477 12/20 0.37
▸ PRSS2 P07478 12/20 0.37
▸ PRSS3 P35030 12/20 0.37
▸ CTSL P07711 1/20 0.36
▸ GAA P10253 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ TMPRSS15 P98073 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11925960 0.94 GAA (0.39) PRSS1PRSS2PRSS3CTSLGAA
SCHEMBL11921764 0.89 TYR (0.36) PRSS1PRSS2PRSS3CTSLGAA
SCHEMBL11921762 0.89 PRSS1 (0.34) PRSS1PRSS2PRSS3CTSLTMPRSS15
SCHEMBL15259406 0.84 GAA (0.36) PRSS1PRSS2PRSS3GAAALDH1A1
SCHEMBL11921753 0.83 PRSS1 (0.38) PRSS1PRSS2PRSS3
SCHEMBL11925961 0.82 TMPRSS15 (0.35) PRSS1PRSS2PRSS3CTSLTMPRSS15
SCHEMBL11921829 0.80 CTSL (0.45) CTSLGAATMPRSS15
SCHEMBL11921765 0.80 MAPT (0.32) PRSS1PRSS2PRSS3CTSLGAA
SCHEMBL11921774 0.79 GAA (0.43) PRSS1PRSS2PRSS3GAAALDH1A1
SCHEMBL20040345 0.79 KMT2A (0.38) GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-07-12 — — US disclosed
US-9868696-B2 Amino acid derivatives and absorbable polymers therefrom Bezwada Biomedial, LLC (US) 2018-01-16 — — US disclosed
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2016-09-08 — — US disclosed
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-06-25 — — US disclosed
US-9012677-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2015-04-21 — — US disclosed
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-03-05 — — US disclosed
US-8901341-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-12-02 — — US disclosed
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2013-09-19 — — US disclosed
US-8461372-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC 2013-06-11 — — US disclosed
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2012-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM SLC7A1, SLC3A2, BCAT2 PRSS1 983/4885PRSS2 1002/4885PRSS3 912/4885
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 PRSS1 878/4885PRSS2 1062/4885PRSS3 966/4885
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 PRSS1 878/4885PRSS2 1062/4885PRSS3 966/4885
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 PRSS1 878/4885PRSS2 1062/4885PRSS3 966/4885
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 PRSS1 878/4885PRSS2 1062/4885PRSS3 966/4885
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 PRSS1 878/4885PRSS2 1062/4885PRSS3 966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback