SCHEMBL11921764

SCHEMBL11921764

Cc1ccc(CC(NC(=O)COC(=O)c2ccc(N=C=O)cc2)C(=O)OCC(=O)Oc2ccc(N=C=O)cc2)cc1OC#N

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TYR P14679 2/20 0.36
▸ GAA P10253 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.33
▸ CTSL P07711 1/20 0.33
▸ PRSS1 P07477 5/20 0.33
▸ PRSS2 P07478 5/20 0.33
▸ PRSS3 P35030 5/20 0.33
▸ TDP1 Q9NUW8 1/20 0.32
▸ MAPT P10636 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ TMPRSS15 P98073 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11921765 0.90 MAPT (0.32) GAACTSLPRSS1PRSS2PRSS3
SCHEMBL11921747 0.89 PRSS1 (0.37) GAAALDH1A1CTSLPRSS1PRSS2
SCHEMBL15259406 0.88 GAA (0.36) TYRGAAALDH1A1PRSS1PRSS2
SCHEMBL11925960 0.87 GAA (0.39) GAAALDH1A1CTSLPRSS1PRSS2
SCHEMBL11921766 0.85 MEN1 (0.35) PRSS1PRSS2PRSS3MAPT
SCHEMBL15258095 0.82 CYP1A2 (0.35) ALDH1A1PRSS1PRSS2PRSS3MAPT
SCHEMBL11921791 0.80 CTSL (0.34) CTSLPRSS1PRSS2PRSS3
SCHEMBL11921762 0.79 PRSS1 (0.34) CTSLPRSS1PRSS2PRSS3TMPRSS15
SCHEMBL15259408 0.78 TMPRSS15 (0.33) GAAPRSS1PRSS2PRSS3MAPT
SCHEMBL11925961 0.76 TMPRSS15 (0.35) CTSLPRSS1PRSS2PRSS3TMPRSS15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-07-12 — — US disclosed
US-9868696-B2 Amino acid derivatives and absorbable polymers therefrom Bezwada Biomedial, LLC (US) 2018-01-16 — — US disclosed
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2016-09-08 — — US disclosed
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-06-25 — — US disclosed
US-9012677-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2015-04-21 — — US disclosed
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-03-05 — — US disclosed
US-8901341-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-12-02 — — US disclosed
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2013-09-19 — — US disclosed
US-8461372-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC 2013-06-11 — — US disclosed
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2012-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM SLC7A1, SLC3A2, BCAT2 TYR 1891/4885GAA 2297/4885ALDH1A1 2903/4885
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 TYR 1897/4885GAA 2510/4885ALDH1A1 3569/4885
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 TYR 1897/4885GAA 2510/4885ALDH1A1 3569/4885
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 TYR 1897/4885GAA 2510/4885ALDH1A1 3569/4885
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 TYR 1897/4885GAA 2510/4885ALDH1A1 3569/4885
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 TYR 1897/4885GAA 2510/4885ALDH1A1 3569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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