SCHEMBL11921788

SCHEMBL11921788

Cc1ccc(CC(NC(=O)C(C)OC(=O)c2ccc(N)cc2)C(=O)OC(C)C(=O)Oc2ccc(N)cc2)cc1N

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LNPEP Q9UIQ6 4/20 0.35
▸ TSHR P16473 1/20 0.35
▸ ERAP2 Q6P179 3/20 0.35
▸ ERAP1 Q9NZ08 1/20 0.35
▸ LMNA P02545 2/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ MAOA P21397 1/20 0.34
▸ PRSS1 P07477 7/20 0.34
▸ TMPRSS15 P98073 7/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ SCN1A P35498 1/20 0.33
▸ SCN2A Q99250 1/20 0.33
▸ SCN3A Q9NY46 1/20 0.33
▸ CTSL P07711 1/20 0.33
▸ TYMS P04818 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11921759 0.91 TSHR (0.42) LNPEPTSHRERAP2ERAP1LMNA
SCHEMBL15259409 0.79 TRPA1 (0.35) TSHRLMNACYP3A4PRSS1TMPRSS15
SCHEMBL11925982 0.77 TSHR (0.41) TSHRPRSS1TMPRSS15CTSL
SCHEMBL11921786 0.76 GAA (0.40) LNPEPTSHRLMNACYP1A2CYP3A4
SCHEMBL16270510 0.75 LMNA (0.49) TSHRLMNACYP1A2CYP3A4MAOA
SCHEMBL11921787 0.74 LMNA (0.36) LNPEPTSHRLMNACYP1A2CYP3A4
SCHEMBL16270243 0.73 LMNA (0.47) TSHRLMNACYP1A2CYP3A4MAOA
SCHEMBL16270205 0.73 LMNA (0.47) TSHRLMNACYP1A2CYP3A4MAOA
SCHEMBL11921777 0.72 CTSL (0.39) TSHRPRSS1CTSL
SCHEMBL11921789 0.72 NPC1 (0.41) TSHRLMNACYP1A2CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-07-12 — — US disclosed
US-9868696-B2 Amino acid derivatives and absorbable polymers therefrom Bezwada Biomedial, LLC (US) 2018-01-16 — — US disclosed
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2016-09-08 — — US disclosed
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2016-09-08 — — US disclosed
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-06-25 — — US disclosed
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-06-25 — — US disclosed
US-9012677-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2015-04-21 — — US disclosed
US-9012677-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2015-04-21 — — US disclosed
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-03-05 — — US disclosed
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-03-05 — — US disclosed
US-8901341-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-12-02 — — US disclosed
US-8901341-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-12-02 — — US disclosed
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2013-09-19 — — US disclosed
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2013-09-19 — — US disclosed
US-8461372-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC 2013-06-11 — — US disclosed
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2012-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM SLC7A1, SLC3A2, BCAT2 LNPEP 589/4885TSHR 2422/4885ERAP2 828/4885
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 LNPEP 568/4885TSHR 2352/4885ERAP2 903/4885
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 LNPEP 568/4885TSHR 2352/4885ERAP2 903/4885
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 LNPEP 568/4885TSHR 2352/4885ERAP2 903/4885
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 LNPEP 568/4885TSHR 2352/4885ERAP2 903/4885
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 LNPEP 568/4885TSHR 2352/4885ERAP2 903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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