SCHEMBL1192279

SCHEMBL1192279

Cc1cccc2c1Cc1ccccc1C2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 3/20 0.41
DRD1 P21728 3/20 0.41
DRD5 P21918 3/20 0.41
DRD3 P35462 3/20 0.41
DRD4 P21917 1/20 0.41
TSHR P16473 3/20 0.41
ACHE P22303 1/20 0.41
ALDH1A1 P00352 3/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP1A2 P05177 2/20 0.39
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HRH1 P35367 1/20 0.36
CYP2A6 P11509 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MAOA P21397 2/20 0.36
MAOB P27338 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6905197 0.86 DRD3 (0.49) DRD2DRD1DRD5DRD3DRD4
SCHEMBL6906227 0.85 DRD1 (0.47) DRD2DRD1DRD5DRD3DRD4
SCHEMBL6904839 0.83 PARP1 (0.38) DRD2DRD1DRD5DRD3DRD4
SCHEMBL6904545 0.82 CYP1A2 (0.43) DRD2DRD1DRD5DRD3DRD4
SCHEMBL11729630 0.81 SMN1; SMN2 (0.34) TSHRALDH1A1SMN1; SMN2
Fluorene SCHEMBL9422463 0.80 PNMT (0.52) ACHEALDH1A1HPGDSMN1; SMN2CYP1A2
SCHEMBL29036487 0.79 CD44 (0.45) TSHRACHEALDH1A1HPGDCYP1A2
SCHEMBL7377994 0.78 ANPEP (0.44) ACHE
SCHEMBL7056082 0.78 BCL2L1 (0.41) DRD2DRD1DRD5DRD3TSHR
SCHEMBL7008462 0.77 CYP1A2 (0.52) TSHRACHEALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9062188-B2 Acrylic rubber composition NOK CORPORATION (JP) 2015-06-23 US disclosed
EP-2568011-B1 ACRYLIC RUBBER COMPOSITION NOK CORP (JP) 2014-11-26 EP disclosed
US-20140005339-A1 ACRYLIC RUBBER COMPOSITION NOK CORPORATION (JP) 2014-01-02 US disclosed
EP-2568011-A1 ACRYLIC RUBBER COMPOSITION NOK Corporation (JP) 2013-03-13 EP disclosed
US-8288483-B2 Diurethane compound, process for producing the same, and acrylic rubber composition containing the same UNIMATEC CO., LTD. (JP) 2012-10-16 US disclosed
US-20110040043-A1 NOVEL DIURETHANE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ACRYLIC RUBBER COMPOSITION CONTAINING THE SAME UNIMATEC CO., LTD. (JP) 2011-02-17 US disclosed
EP-2243770-A1 NOVEL DIURETHANE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ACRYLIC RUBBER COMPOSITION CONTAINING THE SAME Unimatec Co., Ltd. (JP) 2010-10-27 EP disclosed
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110040043-A1 NOVEL DIURETHANE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ACRYLIC RUBBER COMPOSITION CONTAINING THE SAME NCAPH, ODC1, CTH DRD2 181/4885DRD1 187/4885DRD5 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.