SCHEMBL6904545

SCHEMBL6904545

Cc1ccc(C)c2c1Cc1ccccc1C2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
DRD2 P14416 5/20 0.41
DRD1 P21728 5/20 0.41
DRD5 P21918 5/20 0.41
DRD3 P35462 5/20 0.41
DRD4 P21917 2/20 0.41
TSHR P16473 3/20 0.40
ACHE P22303 1/20 0.40
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP2A6 P11509 1/20 0.37
AKT1 P31749 1/20 0.36
AKT2 P31751 1/20 0.36
AKT3 Q9Y243 1/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1192279 0.82 DRD2 (0.41) CYP1A2DRD2DRD1DRD5DRD3
SCHEMBL6905197 0.79 DRD3 (0.49) CYP1A2DRD2DRD1DRD5DRD3
SCHEMBL28974754 0.78 CYP1A2 (0.43) CYP1A2DRD2DRD1DRD5DRD3
SCHEMBL8857148 0.77 PNMT (0.43) TSHRACHEALDH1A1HPGDSMN1; SMN2
SCHEMBL29859431 0.77 PNMT (0.43) TSHRACHEALDH1A1HPGDSMN1; SMN2
SCHEMBL23739814 0.74 CYP1A2 (0.40) CYP1A2DRD2DRD1DRD5DRD3
SCHEMBL135721 0.74 PNMT (0.53) DRD2DRD3DRD4TSHRACHE
SCHEMBL1790495 0.73 CYP1A2 (0.50) CYP1A2DRD2DRD1DRD5DRD3
SCHEMBL11981456 0.73 MAOA (0.52) SMN1; SMN2MAOAMAOB
Fluorene SCHEMBL9422463 0.72 PNMT (0.52) CYP1A2ACHEALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed