Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.57 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.57 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.57 |
| ▸ | MLNR | O43193 | 1/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | USP1 | O94782 | 1/20 | 0.57 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929305 | 0.92 | HTR2A (0.68) | SIGMAR1CYP2D6OPRM1CACNA1GCACNA1H | |
| SCHEMBL10281721 | 0.87 | SIGMAR1 (0.55) | SIGMAR1CYP2D6OPRM1CACNA1GCACNA1H | |
| SCHEMBL24708799 | 0.82 | CACNA1G (0.84) | SIGMAR1CYP2D6OPRM1CACNA1GCACNA1H | |
| SCHEMBL31000433 | 0.82 | CACNA1G (0.84) | SIGMAR1CYP2D6OPRM1CACNA1GCACNA1H | |
| SCHEMBL11925195 | 0.81 | SLC6A2 (0.65) | SIGMAR1CYP2D6OPRM1CACNA1GCACNA1H | |
| SCHEMBL10281563 | 0.81 | OPRM1 (0.65) | SIGMAR1CYP2D6OPRM1CACNA1GCACNA1H | |
| SCHEMBL14186021 | 0.79 | DRD2 (0.57) | CYP2D6OPRM1CACNA1GCACNA1HDRD2 | |
| SCHEMBL11841717 | 0.79 | DRD2 (0.64) | CYP2D6OPRM1CACNA1GCACNA1HSLC6A2 | |
| SCHEMBL20369282 | 0.79 | DRD2 (0.57) | CYP2D6CACNA1GCACNA1HSLC6A2DRD2 | |
| SCHEMBL20368998 | 0.78 | SLC6A2 (0.62) | SIGMAR1CYP2D6OPRM1CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180194732-A1 | MULTI-API LOADING PRODRUGS | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2018-07-12 | — | — | US | disclosed |
| US-20160024011-A1 | Multi-API Loading Prodrugs | ALKERMES PHARMA IRELAND LTD (IE) | 2016-01-28 | — | — | US | disclosed |
| US-20120202823-A1 | Multi-API Loading Prodrugs | ALKERMES, INC. | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024011-A1 | Multi-API Loading Prodrugs | AADAC, PAICS, ABCG2 | SIGMAR1 140/4885CYP2D6 119/4885OPRM1 288/4885 |
| US-20120202823-A1 | Multi-API Loading Prodrugs | AADAC, PAICS, ABCG2 | SIGMAR1 140/4885CYP2D6 119/4885OPRM1 288/4885 |
| US-20180194732-A1 | MULTI-API LOADING PRODRUGS | AADAC, PAICS, ABCG2 | SIGMAR1 140/4885CYP2D6 119/4885OPRM1 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.