Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | LYN | P07948 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929145 | 0.90 | L3MBTL1 (0.58) | L3MBTL1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10281469 | 0.85 | L3MBTL1 (0.51) | L3MBTL1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18585286 | 0.80 | MEN1 (0.46) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11925061 | 0.78 | ALDH1A1 (0.54) | L3MBTL1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8877704 | 0.77 | HSD17B10 (0.51) | L3MBTL1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27972762 | 0.75 | ALDH1A1 (0.54) | L3MBTL1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29274435 | 0.75 | ATM (0.45) | L3MBTL1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18586757 | 0.74 | LMNA (0.53) | L3MBTL1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22088833 | 0.74 | KMT2A (0.45) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8042390 | 0.72 | KMT2A (0.81) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180194732-A1 | MULTI-API LOADING PRODRUGS | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2018-07-12 | — | — | US | disclosed |
| US-20120202823-A1 | Multi-API Loading Prodrugs | ALKERMES, INC. | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202823-A1 | Multi-API Loading Prodrugs | AADAC, PAICS, ABCG2 | L3MBTL1 3008/4885KMT2A 652/4885MEN1 2927/4885 |
| US-20180194732-A1 | MULTI-API LOADING PRODRUGS | AADAC, PAICS, ABCG2 | L3MBTL1 3008/4885KMT2A 652/4885MEN1 2927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.