SCHEMBL27972762

SCHEMBL27972762

O=C(c1cc(Cl)ccc1O)N(CCO)c1ccc([N+](=O)[O-])cc1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
KMT2A Q03164 2/20 0.54
LMNA P02545 2/20 0.54
MAPT P10636 2/20 0.54
PKM P14618 2/20 0.54
MAPK1 P28482 2/20 0.54
BLM P54132 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
KDR P35968 2/20 0.54
MEN1 O00255 1/20 0.54
AURKA O14965 1/20 0.54
NPC1 O15118 1/20 0.54
PDPK1 O15530 1/20 0.54
JAK2 O60674 1/20 0.54
GMNN O75496 1/20 0.54
EGFR P00533 1/20 0.54
TP53 P04637 1/20 0.54
CYP1A2 P05177 1/20 0.54
LYN P07948 1/20 0.54
CHRM2 P08172 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11929145 0.82 L3MBTL1 (0.58) ALDH1A1KMT2ALMNAMAPTPKM
SCHEMBL11925061 0.80 ALDH1A1 (0.54) ALDH1A1KMT2ALMNAMAPTPKM
SCHEMBL18586757 0.79 LMNA (0.53) ALDH1A1KMT2ALMNAMAPTPKM
SCHEMBL11929092 0.75 L3MBTL1 (0.58) ALDH1A1KMT2ALMNAMAPTPKM
SCHEMBL1984158 0.75 HSD17B10 (0.51) ALDH1A1KMT2ALMNAMAPTTDP1
SCHEMBL10281469 0.73 L3MBTL1 (0.51) ALDH1A1KMT2ALMNAMAPTPKM
SCHEMBL6814695 0.72 ALDH1A1 (0.67) ALDH1A1KMT2ALMNAMAPTTDP1
Niclosamide SCHEMBL1871351 0.71 MEN1 (0.85) ALDH1A1KMT2ALMNAMAPTPKM
Niclosamide SCHEMBL29361726 0.71 MEN1 (0.85) ALDH1A1KMT2ALMNAMAPTPKM
Niclosamide SCHEMBL2060904 0.70 KMT2A (0.89) ALDH1A1KMT2ALMNAMAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108719290-B Molluscacide ethanolamine salt dry suspending agent and preparation method thereof 青岛润农化工有限公司 2023-07-21 CN disclosed
CN-114208825-A Preparation process of niclosamide ethanolamine salt granules 恒诚制药集团淮南有限公司 2022-03-22 CN disclosed
CN-110637817-A Pesticide composition based on niclosamide ethanolamine salt and preparation method thereof 恒诚制药集团淮南有限公司 2020-01-03 CN disclosed
CN-104186542-B A kind of environment-friendly type Pomacea canaliculata prevention and control agent and application thereof SOUTH CHINA AGRICULTURAL UNIVERSITY (CN) 2017-01-04 CN disclosed
CN-106234364-A A kind of kill spiral shell granule with what wood sawdust made main carriers 邓付圆 2016-12-21 CN disclosed
CN-103891720-B A kind ofly kill spiral shell composition containing the composite of the withered prestige of spiral shell SHANXI THOMPSON BIOLOGICAL TECHNOLOGY CO., LTD. (CN) 2016-02-17 CN disclosed
CN-104186542-A Environment-friendly pomacea canaliculata prevention and control agent and applications thereof UNIV SOUTH CHINA AGRICULT 2014-12-10 CN disclosed
CN-103891720-A Luokuwei-containing compound gastropod-killing composition SHAANXI TANGPUSEN BIOTECH CO 2014-07-02 CN disclosed