Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 3/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11957638 | 0.78 | KIF11 (0.47) | ABCC9KCNJ11KIF11CYP2A6ALDH1A1 | |
| SCHEMBL11932878 | 0.76 | MAPT (0.38) | ALDH1A1HTTCA2CA1LMNA | |
| SCHEMBL11932877 | 0.75 | MEN1 (0.38) | ABCC9KCNJ11ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11939097 | 0.75 | KIF11 (0.44) | ABCC9KCNJ11KIF11CYP2A6ALDH1A1 | |
| SCHEMBL19966743 | 0.75 | KIF11 (0.44) | ABCC9KCNJ11KIF11CYP2A6ALDH1A1 | |
| SCHEMBL17680380 | 0.73 | KIF11 (0.57) | ABCC9KCNJ11KIF11CYP2A6ALDH1A1 | |
| SCHEMBL19966755 | 0.72 | ABCC9 (0.51) | ABCC9KCNJ11KIF11CYP2A6ALDH1A1 | |
| SCHEMBL5360276 | 0.70 | KIF11 (0.47) | KIF11CYP2A6ALDH1A1HTTCA2 | |
| SCHEMBL19708127 | 0.69 | SLC22A12 (0.40) | ABCC9KCNJ11KIF11CYP2A6ALDH1A1 | |
| SCHEMBL19707399 | 0.69 | MAPT (0.45) | ABCC9KCNJ11ALDH1A1HTTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315957-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | TONG YOUZHI (CN) | 2014-10-23 | — | — | US | disclosed |
| US-8809550-B2 | Androgen receptor antagonists and uses thereof | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2014-08-19 | — | — | US | disclosed |
| US-20120172406-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | Tong, Youzhi (CN) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172406-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | AR, SHBG, MUSK | ABCC9 4464/4885KCNJ11 3583/4885KIF11 3545/4885 |
| US-20140315957-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | AR, SHBG, MUSK | ABCC9 4464/4885KCNJ11 3583/4885KIF11 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.