SCHEMBL11932967

SCHEMBL11932967

CC(CO)C1OC(C)(C)OC1C(O)CO

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ THPO P40225 1/20 0.37
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ MANBA O00462 1/20 0.32
▸ THRB P10828 1/20 0.32
▸ HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1984099 0.89 LMNA (0.41) LMNACYP1A2THPOMEN1KMT2A
SCHEMBL7147890 0.89 LMNA (0.41) LMNACYP1A2THPOMEN1KMT2A
SCHEMBL1301822 0.89 LMNA (0.41) LMNACYP1A2THPOMEN1KMT2A
SCHEMBL6676888 0.89 LMNA (0.41) LMNACYP1A2THPOMEN1KMT2A
SCHEMBL12018358 0.89 LMNA (0.41) LMNACYP1A2THPOMEN1KMT2A
SCHEMBL18596140 0.89 LMNA (0.41) LMNACYP1A2THPOMEN1KMT2A
SCHEMBL12604242 0.89 TSHR (0.32) —
SCHEMBL2756249 0.89 LMNA (0.41) LMNACYP1A2THPOMEN1KMT2A
SCHEMBL2367932 0.89 LMNA (0.41) LMNACYP1A2THPOMEN1KMT2A
SCHEMBL15678411 0.89 LMNA (0.41) LMNACYP1A2THPOMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120172631-A1 PHOSPHATIDYL OLIGOGLYCEROLS MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E. V. (DE) 2012-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120172631-A1 PHOSPHATIDYL OLIGOGLYCEROLS PHOSPHO1, SGMS2, LIPG LMNA 2170/4885CYP1A2 615/4885THPO 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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