SCHEMBL11933009

SCHEMBL11933009

c1ccc(-c2cc(-c3ccccc3)nc(-n3c4ccccc4c4c5oc6c(ccc7c6c6ccccc6n7-c6nc(-c7ccccc7)cc(-c7ccccc7)n6)c5ccc43)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.36
ALDH1A1 P00352 4/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
TSHR P16473 4/20 0.36
MAPK1 P28482 3/20 0.36
NPSR1 Q6W5P4 3/20 0.36
POLB P06746 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
ALOX12 P18054 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
KDM4E B2RXH2 2/20 0.35
ADORA1 P30542 3/20 0.35
HPGD P15428 2/20 0.35
ADORA2A P29274 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16484295 0.95 L3MBTL1 (0.40) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL17990653 0.94 CYP1A1 (0.40) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL22708577 0.93 MAPT (0.34) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL13183745 0.93 MAPT (0.34) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL16437599 0.92 KMT2A (0.32) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL9881133 0.91 MEN1 (0.33) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL15625580 0.91 MEN1 (0.33) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL16437595 0.89 TDP1 (0.32) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL9890028 0.89 MAPT (0.32) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL22708578 0.88 KDM4E (0.32) MAPTALDH1A1MAPK1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190194219-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-06-27 US disclosed
US-9290513-B2 Compound containing 5-membered heterocycles, organic electronic device using same, and terminal comprising the latter DUK SAN NEOLUX CO., LTD. (KR) 2016-03-22 US disclosed
US-9290513-B2 Compound containing 5-membered heterocycles, organic electronic device using same, and terminal comprising the latter DUK SAN NEOLUX CO., LTD. (KR) 2016-03-22 US disclosed
US-20150307514-A1 COMPOUND CONTAINING 5-MEMBERED HETEROCYCLES, ORGANIC ELECTRONIC DEVICE USING SAME, AND TERMINAL COMPRISING THE LATTER DUK SAN NEOLUX CO., LTD. (KR) 2015-10-29 US disclosed
US-20150307514-A1 COMPOUND CONTAINING 5-MEMBERED HETEROCYCLES, ORGANIC ELECTRONIC DEVICE USING SAME, AND TERMINAL COMPRISING THE LATTER DUK SAN NEOLUX CO., LTD. (KR) 2015-10-29 US disclosed
US-9079920-B2 Compound containing 5-membered heterocycles, organic light-emitting device using same, and terminal comprising the latter DUK SAN NEOLUX CO., LTD. (KR) 2015-07-14 US disclosed
US-9079920-B2 Compound containing 5-membered heterocycles, organic light-emitting device using same, and terminal comprising the latter DUK SAN NEOLUX CO., LTD. (KR) 2015-07-14 US disclosed
US-20120168734-A1 COMPOUND CONTAINING 5-MEMBERED HETEROCYCLES, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND TERMINAL COMPRISING THE LATTER DUKSAN HIGH METAL CO., LTD. (KR) 2012-07-05 US disclosed
US-20120168734-A1 COMPOUND CONTAINING 5-MEMBERED HETEROCYCLES, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND TERMINAL COMPRISING THE LATTER DUKSAN HIGH METAL CO., LTD. (KR) 2012-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120168734-A1 COMPOUND CONTAINING 5-MEMBERED HETEROCYCLES, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND TERMINAL COMPRISING THE LATTER ORC3, OR10J3, SUN2 MAPT 2781/4885ALDH1A1 472/4885MEN1 653/4885
US-20150307514-A1 COMPOUND CONTAINING 5-MEMBERED HETEROCYCLES, ORGANIC ELECTRONIC DEVICE USING SAME, AND TERMINAL COMPRISING THE LATTER EMC2, AOC2, MCM5 MAPT 4014/4885ALDH1A1 610/4885MEN1 257/4885
US-20190194219-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH SAME OR10J3, EML4, AOC2 MAPT 1992/4885ALDH1A1 174/4885MEN1 1701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.