SCHEMBL11938185

SCHEMBL11938185

CC(C)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(C)C3=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 1/20 0.45
▸ MEN1 O00255 6/20 0.44
▸ KMT2A Q03164 6/20 0.44
▸ ALDH1A1 P00352 5/20 0.44
▸ USP2 O75604 2/20 0.44
▸ KEAP1 Q14145 2/20 0.44
▸ NFE2L2 Q16236 2/20 0.44
▸ HPGD P15428 2/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ ATM Q13315 1/20 0.44
▸ POLB P06746 1/20 0.42
▸ PRMT1 Q99873 1/20 0.42
▸ TERT O14746 4/20 0.40
▸ L3MBTL1 Q9Y468 3/20 0.38
▸ MAPT P10636 2/20 0.38
▸ HSD17B10 Q99714 2/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ NPC1 O15118 2/20 0.37
▸ RAB9A P51151 2/20 0.37
▸ APP P05067 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19101497 0.93 TERT (0.46) CASP3MEN1KMT2AALDH1A1USP2
SCHEMBL19101527 0.93 TERT (0.46) CASP3MEN1KMT2AALDH1A1USP2
SCHEMBL14163601 0.93 TERT (0.46) CASP3MEN1KMT2AALDH1A1USP2
SCHEMBL19101440 0.93 TERT (0.46) CASP3MEN1KMT2AALDH1A1USP2
SCHEMBL19101477 0.93 TERT (0.46) CASP3MEN1KMT2AALDH1A1USP2
SCHEMBL19101441 0.93 TERT (0.46) CASP3MEN1KMT2AALDH1A1USP2
SCHEMBL12381797 0.91 NPC1 (0.42) MEN1KMT2AALDH1A1USP2KDM4E
SCHEMBL10018460 0.85 KDM4E (0.40) MEN1KMT2AALDH1A1USP2HPGD
SCHEMBL127059 0.84 MEN1 (0.55) CASP3MEN1KMT2AALDH1A1USP2
SCHEMBL30937815 0.84 MEN1 (0.55) CASP3MEN1KMT2AALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11649254-B2 Compound, a display panel and an electronic device Wuhan Tianma Microelectronics Co., Ltd. Shanghai Branch (CN) 2023-05-16 — — US disclosed
US-11649254-B2 Compound, a display panel and an electronic device Wuhan Tianma Microelectronics Co., Ltd. Shanghai Branch (CN) 2023-05-16 — — US disclosed
US-20200270278-A1 COMPOUND, A DISPLAY PANEL AND AN ELECTRONIC DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-08-27 — — US disclosed
US-9320686-B2 Dental materials based on compounds having debonding-on-demand properties IVOCLAR VIVADENT AG (LI) 2016-04-26 — — US disclosed
US-20140371341-A1 DENTAL MATERIALS BASED ON COMPOUNDS HAVING DEBONDING-ON-DEMAND PROPERTIES IVOCLAR VIVADENT AG (LI) 2014-12-18 — — US disclosed
WO-2013034778-A2 DENTAL MATERIALS BASED ON COMPOUNDS HAVING DEBONDING-ON-DEMAND PROPERTIES IVOCLAR VIVADENT AG (LI) 2013-03-14 — — WO disclosed
US-8211558-B2 Crosslinked polymer electrolyte and method for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-03 — — US disclosed
US-20110130538-A1 PHOTOLYTIC ACID-GENERATING POLYMERS AND MONOMERS FOR THEIR CONSTRUCTION THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) 2011-06-02 — — US disclosed
US-20090274943-A1 CROSSLINKED POLYMER ELECTROLYTE AND METHOD FOR PRODUCING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-11-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140371341-A1 DENTAL MATERIALS BASED ON COMPOUNDS HAVING DEBONDING-ON-DEMAND PROPERTIES NR2E1, RCOR3, NR0B1 CASP3 1323/4885MEN1 2091/4885KMT2A 252/4885
US-20110130538-A1 PHOTOLYTIC ACID-GENERATING POLYMERS AND MONOMERS FOR THEIR CONSTRUCTION PPOX, ALAD, PGAM1 CASP3 4612/4885MEN1 4219/4885KMT2A 2421/4885
US-11649254-B2 Compound, a display panel and an electronic device TEAD2, OCIAD2, TEAD4 CASP3 2246/4885MEN1 4643/4885KMT2A 3001/4885
US-20200270278-A1 COMPOUND, A DISPLAY PANEL AND AN ELECTRONIC DEVICE TEAD2, OCIAD2, TEAD4 CASP3 2246/4885MEN1 4643/4885KMT2A 3001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback