Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SOD1 | P00441 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11941542 | 0.85 | GRM2 (0.49) | ALDH1A1KDM4ESMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL28306905 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL26986055 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL11943318 | 0.81 | LMNA (0.45) | ALDH1A1KDM4ESMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL18320646 | 0.81 | ALDH2 (0.45) | ALDH1A1KDM4ESMN1; SMN2TSHRACACB | |
| SCHEMBL18320474 | 0.80 | ACACB (0.45) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL14166366 | 0.79 | ACACB (0.46) | ALDH1A1KDM4ESMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL15295402 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KDM4ESMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL11937220 | 0.78 | FFAR1 (0.49) | ALDH1A1SMN1; SMN2L3MBTL1TSHRACACB | |
| SCHEMBL14166208 | 0.78 | ACACB (0.45) | ALDH1A1KDM4ESMN1; SMN2MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227456-B2 | Pharmaceutical composition for preventing and treating metabolic bone diseases containing alpha-arylmethoxyacrylate derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-07-24 | — | — | US | disclosed |
| US-20100256367-A1 | Pharmaceutical Composition For Preventing and Treating Metabolic Bone Diseases Containing Alpha-Arylmethoxyactylate Derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256367-A1 | Pharmaceutical Composition For Preventing and Treating Metabolic Bone Diseases Containing Alpha-Arylmethoxyactylate Derivatives | ARSA, BMP2, BMP1 | ALDH1A1 721/4885KDM4E 1873/4885SMN1; SMN2 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.