Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | FBP1 | P09467 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | MC5R | P33032 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1419448 | 0.88 | FBP1 (0.50) | CYP1A2CYP2D6CYP3A4CYP2C19MAPK1 | |
| SCHEMBL1194363 | 0.85 | FBP1 (0.47) | CYP1A2CYP2D6CYP3A4CYP2C19MAPK1 | |
| SCHEMBL1193757 | 0.85 | FBP1 (0.54) | CYP1A2CYP2D6CYP3A4CYP2C19MAPK1 | |
| SCHEMBL1193524 | 0.82 | FBP1 (0.51) | CYP1A2CYP2D6CYP3A4CYP2C19MAPK1 | |
| SCHEMBL1820077 | 0.81 | ALDH1A1 (0.41) | MAPK1L3MBTL1ALDH1A1HPGDALOX15 | |
| SCHEMBL1193557 | 0.80 | ALDH1A1 (0.49) | CYP1A2CYP2D6CYP3A4CYP2C19MAPK1 | |
| SCHEMBL3477077 | 0.80 | L3MBTL1 (0.47) | CYP1A2CYP2D6CYP3A4CYP2C19MAPK1 | |
| SCHEMBL1194508 | 0.79 | ALDH1A1 (0.51) | CYP1A2CYP2D6CYP3A4CYP2C19MAPK1 | |
| SCHEMBL1194379 | 0.78 | HTR1A (0.50) | CYP1A2CYP2D6CYP3A4CYP2C19MAPK1 | |
| SCHEMBL1194268 | 0.78 | FBP1 (0.50) | CYP1A2CYP2D6CYP3A4CYP2C19MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796387-B2 | Rubber composition | BRIDGESTONE CORPORATION (JP) | 2014-08-05 | — | — | US | disclosed |
| US-8609252-B2 | Rubber composition | BRIDGESTONE CORPORATION (JP) | 2013-12-17 | — | — | US | disclosed |
| EP-2233521-B1 | RUBBER COMPOSITION | BRIDGESTONE CORP (JP) | 2013-09-04 | — | — | EP | disclosed |
| EP-2316879-B1 | RUBBER COMPOSITION | BRIDGESTONE CORP (JP) | 2013-08-07 | — | — | EP | disclosed |
| US-20110184109-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | US | disclosed |
| US-20110172339-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110166277-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2011-07-07 | — | — | US | disclosed |
| US-20110124787-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2011-05-26 | — | — | US | disclosed |
| US-20110118397-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-2316881-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2011-05-04 | — | — | EP | disclosed |
| EP-2316880-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2011-05-04 | — | — | EP | disclosed |
| EP-2316879-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2011-05-04 | — | — | EP | disclosed |
| EP-2301997-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2011-03-30 | — | — | EP | disclosed |
| EP-2298834-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2011-03-23 | — | — | EP | disclosed |
| US-20110034638-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2011-02-10 | — | — | US | disclosed |
| EP-2233521-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2010-09-29 | — | — | EP | disclosed |