Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11947657 | 0.87 | DPP4 (0.47) | SMN1; SMN2NPC1RAB9AGAANPSR1 | |
| SCHEMBL11947648 | 0.86 | KMT2A (0.63) | POLBHTTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11947659 | 0.86 | HSD17B10 (0.56) | POLBKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11947662 | 0.85 | HPGD (0.49) | SMN1; SMN2NPC1RAB9ALMNAGAA | |
| SCHEMBL8065024 | 0.82 | POLB (0.54) | POLBGFERHTTGRM5KDM4E | |
| SCHEMBL8065026 | 0.82 | POLB (0.54) | POLBGFERHTTGRM5KDM4E | |
| SCHEMBL9727540 | 0.79 | NPSR1 (0.68) | GRM5KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL34468319 | 0.78 | MEN1 (0.53) | POLBGFERGRM5KDM4EMAPT | |
| SCHEMBL31627496 | 0.78 | MEN1 (0.53) | POLBGFERGRM5KDM4EMAPT | |
| SCHEMBL27610366 | 0.76 | MAPT (0.74) | HTTKDM4EALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232315-B2 | Methods for treating drug addiction and improving addiction-related behavior | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2012-07-31 | — | — | US | disclosed |
| US-8232315-B2 | Methods for treating drug addiction and improving addiction-related behavior | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2012-07-31 | — | — | US | disclosed |
| US-20100331332-A1 | METHODS FOR TREATING DRUG ADDICTION AND IMPROVING ADDICTION-RELATED BEHAVIOR | SK HOLDINGS CO., LTD. (KR) | 2010-12-30 | — | — | US | disclosed |
| US-20100331332-A1 | METHODS FOR TREATING DRUG ADDICTION AND IMPROVING ADDICTION-RELATED BEHAVIOR | SK HOLDINGS CO., LTD. (KR) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331332-A1 | METHODS FOR TREATING DRUG ADDICTION AND IMPROVING ADDICTION-RELATED BEHAVIOR | CES2, SLC6A3, CHAT | POLB 3466/4885GFER 2410/4885HTT 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.