Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | FGB | P02675 | 1/20 | 0.34 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393280 | 0.90 | SMN1; SMN2 (0.33) | MTNR1AMTNR1BTP53KMT2AMEN1 | |
| SCHEMBL4391667 | 0.74 | PRCP (0.51) | MTNR1AMTNR1BMAPT | |
| SCHEMBL7094962 | 0.63 | MAPT (0.56) | MTNR1AMTNR1BMAPTTP53KMT2A | |
| SCHEMBL30427144 | 0.63 | CETP (0.52) | MTNR1AMTNR1BMAPTTP53KMT2A | |
| SCHEMBL28999657 | 0.63 | CETP (0.52) | MTNR1AMTNR1BMAPTTP53KMT2A | |
| SCHEMBL6986366 | 0.63 | MAPT (0.46) | MTNR1AMTNR1BMAPTKMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL27509223 | 0.62 | MAPT (0.55) | MTNR1AMTNR1BMAPTTP53KMT2A | |
| SCHEMBL7010711 | 0.62 | MTNR1A (0.51) | MTNR1AMTNR1BMAPTTP53KMT2A | |
| SCHEMBL7237888 | 0.60 | MTNR1A (0.59) | MTNR1AMTNR1BMAPTTP53KMT2A | |
| SCHEMBL7006460 | 0.60 | MTNR1A (0.59) | MTNR1AMTNR1BMAPTTP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232399-B2 | Chiral ligands, their preparation and uses thereof in asymmetric reactions | Li, Chao-Jun (CA) | 2012-07-31 | — | — | US | disclosed |