Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | FGB | P02675 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11948858 | 0.90 | MTNR1A (0.39) | TP53MAPK1MTNR1AMTNR1BMEN1 | |
| SCHEMBL13651011 | 0.68 | DHFR (0.36) | SMN1; SMN2DRD2DRD1MEN1KMT2A | |
| SCHEMBL4391667 | 0.64 | PRCP (0.51) | DRD2DRD1MTNR1AMTNR1B | |
| SCHEMBL1446528 | 0.62 | MAPT (0.63) | SMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL29820187 | 0.62 | MAPT (0.63) | SMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL15285233 | 0.61 | MAPT (0.47) | SMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL8731312 | 0.61 | NCEH1 (0.47) | SMN1; SMN2MAPK1MEN1KMT2ACASP1 | |
| SCHEMBL20563011 | 0.60 | LMNA (0.49) | SMN1; SMN2TP53MEN1KMT2AHSD17B10 | |
| SCHEMBL20562339 | 0.60 | MAPT (0.46) | SMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL29937151 | 0.60 | SMN1; SMN2 (0.56) | SMN1; SMN2TP53MAPK1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232399-B2 | Chiral ligands, their preparation and uses thereof in asymmetric reactions | Li, Chao-Jun (CA) | 2012-07-31 | — | — | US | disclosed |
| US-8232399-B2 | Chiral ligands, their preparation and uses thereof in asymmetric reactions | Li, Chao-Jun (CA) | 2012-07-31 | — | — | US | disclosed |
| US-20090306390-A1 | CHIRAL LIGANDS, THEIR PREPARATION AND USES THEREOF IN ASYMMETRIC REACTIONS | CHAO-JUN LI (CA) | 2009-12-10 | — | — | US | disclosed |
| WO-2007098608-A1 | CHIRAL LIGANDS, THEIR PREPARATION AND USES THEREOF IN ASSYMETRIC REACTIONS | LI CHAO-JUN (CA) | 2007-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306390-A1 | CHIRAL LIGANDS, THEIR PREPARATION AND USES THEREOF IN ASYMMETRIC REACTIONS | OR10J3, C1R, C3AR1 | SMN1; SMN2 4348/4885TP53 2150/4885DRD2 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.