Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 2/20 | 0.43 |
| ▸ | SAT1 | P21673 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | MVD | P53602 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 3/20 | 0.33 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11952573 | 0.87 | BTN3A1 (0.58) | BTN3A1LPAR3LPAR1LPAR2GGPS1 | |
| SCHEMBL11952589 | 0.86 | ALDH1A1 (0.50) | BTN3A1SAT1MVDALDH1A1 | |
| SCHEMBL18258054 | 0.80 | PLA2G2A (0.43) | BTN3A1LPAR3LPAR1LPAR2PAOX | |
| SCHEMBL17754043 | 0.79 | LPAR3 (0.57) | LPAR3LPAR1LPAR2PAOXALDH1A1 | |
| SCHEMBL11952605 | 0.77 | SAT1 (0.42) | BTN3A1SAT1LPAR3LPAR1LPAR2 | |
| SCHEMBL14099511 | 0.73 | PLA2G4A (0.40) | SAT1LPAR3LPAR1LPAR2PAOX | |
| SCHEMBL16792076 | 0.72 | LPAR3 (0.54) | BTN3A1LPAR3LPAR1LPAR2PAOX | |
| SCHEMBL11952594 | 0.71 | SAT1 (0.38) | BTN3A1SAT1LPAR3LPAR1LPAR2 | |
| SCHEMBL91094 | 0.71 | BTN3A1 (0.41) | BTN3A1SAT1MVDALDH1A1 | |
| SCHEMBL11952592 | 0.70 | MVD (0.54) | BTN3A1LPAR3LPAR1LPAR2GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120196835-A1 | ENZYME INHIBITING COMPOUNDS AND METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196835-A1 | ENZYME INHIBITING COMPOUNDS AND METHODS | COASY, FADS2, FDPS | BTN3A1 4124/4885SAT1 2039/4885LPAR3 3076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.