SCHEMBL11953201

SCHEMBL11953201

Cc1cnc2sc(-c3ccncc3OCC(F)F)nc2c1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.38
F2RL3 Q96RI0 4/20 0.36
BUB1 O43683 7/20 0.35
DYRK1A Q13627 3/20 0.32
MAPT P10636 1/20 0.32
GSK3B P49841 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11953198 0.86 S1PR1 (0.38) DYRK1AMAPT
SCHEMBL1665866 0.85 BUB1 (0.34) CYP17A1BUB1
SCHEMBL11953200 0.85 DYRK1A (0.38) F2RL3DYRK1AMAPT
SCHEMBL11953196 0.78 LATS1 (0.36) MAPT
SCHEMBL10249232 0.76 BUB1 (0.39) CYP17A1BUB1MAPTGSK3B
SCHEMBL11953197 0.76 DYRK1A (0.38) DYRK1A
SCHEMBL11953203 0.76 LMNA (0.32) DYRK1AMAPT
SCHEMBL4544554 0.76 SGMS2 (0.39) CYP17A1BUB1MAPTGSK3B
SCHEMBL11953202 0.74 CCR1 (0.32) DYRK1AMAPT
SCHEMBL16803713 0.74 DYRK1A (0.33) DYRK1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8742112-B2 Heterocyclic compound and its use for control of an arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-06-03 US disclosed
US-20120196891-A1 HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120196891-A1 HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST HAAO, DDT, ACHE CYP17A1 459/4885F2RL3 2880/4885BUB1 3350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.