Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CBS | P35520 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967922 | 0.85 | NPC1 (0.44) | CDK1ERN1LMNAMAPT | |
| SCHEMBL17903485 | 0.83 | ERN1 (0.37) | CDK1ERN1PIM1 | |
| SCHEMBL5673519 | 0.82 | PTGS2 (0.50) | CDK1LMNA | |
| SCHEMBL7251486 | 0.78 | PTGS2 (0.49) | CDK1LMNA | |
| SCHEMBL882872 | 0.78 | CYP2C19 (0.39) | CDK1ERN1LMNA | |
| SCHEMBL3965795 | 0.77 | ERN1 (0.42) | CDK1ERN1LMNAMAPT | |
| SCHEMBL28528307 | 0.74 | NPC1 (0.41) | CDK1ERN1LMNAMAPT | |
| SCHEMBL29942736 | 0.74 | KDM4E (0.57) | CDK1ERN1LMNAMAPT | |
| SCHEMBL18218320 | 0.74 | KDM4E (0.57) | CDK1ERN1LMNAMAPT | |
| SCHEMBL23043240 | 0.74 | CDK1 (0.80) | CDK1ERN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414743-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2019-09-17 | — | — | US | disclosed |
| US-20160159763-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| US-20160159763-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| US-9279082-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2016-03-08 | — | — | US | disclosed |
| US-9279082-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2016-03-08 | — | — | US | disclosed |
| EP-2665798-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-10-08 | — | — | EP | disclosed |
| US-20130308081-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2013-11-21 | — | — | US | disclosed |
| WO-2012097858-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2012-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10414743-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | VCL, LPXN, ACP3 | CDK1 141/4885TNKS2 1647/4885ERN1 3042/4885 |
| US-20160159763-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, LPXN, LCP1 | CDK1 195/4885TNKS2 1568/4885ERN1 2793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.