Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5882422 | 0.91 | ERN1 (0.41) | ERN1LMNAMAPTCDK1DHFR | |
| SCHEMBL7251486 | 0.89 | PTGS2 (0.49) | LMNACDK1ALOX5 | |
| SCHEMBL3967922 | 0.86 | NPC1 (0.44) | ERN1LMNAMAPTCDK1ALOX5 | |
| SCHEMBL5673519 | 0.83 | PTGS2 (0.50) | LMNACDK1ALOX5 | |
| SCHEMBL5883620 | 0.82 | ERN1 (0.47) | ERN1LMNAMAPTCDK1CNR1 | |
| SCHEMBL5883032 | 0.82 | ERN1 (0.62) | ERN1PTPN1PTPN11 | |
| SCHEMBL15591003 | 0.81 | ERN1 (0.55) | ERN1LMNAMAPTPTPN1PTPN11 | |
| SCHEMBL19792610 | 0.81 | ERN1 (0.55) | ERN1LMNAMAPT | |
| SCHEMBL1023215 | 0.80 | DHFR (0.45) | DHFRPTPN1PTPN11CNR1CNR2 | |
| SCHEMBL3966884 | 0.79 | ERN1 (0.47) | ERN1LMNAMAPTCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101514212-B | Synthetic method of pyridine-2''amino-2'-hydroxybenzene methanol phenylcarbinol boric acid ester compound | UNIV LIAONING | 2011-11-09 | — | — | CN | claimed |
| EP-1992630-B1 | Covalently fixed non-metallocenes, method for the production thereof and their use for polymerizing olefins | TICONA GMBH (DE) | 2012-10-31 | — | — | EP | disclosed |
| CN-101514212-B | Synthetic method of pyridine-2''amino-2'-hydroxybenzene methanol phenylcarbinol boric acid ester compound | UNIV LIAONING | 2011-11-09 | — | — | CN | disclosed |
| CN-101514212-A | Pyridine-2''amino-2'-hydroxybenzene methanol phenylcarbinol boric acid ester compound and synthetic method thereof | UNIV LIAONING (CN) | 2009-08-26 | — | — | CN | disclosed |
| EP-1480987-B1 | COVALENTLY FIXED NON-METALLOCENES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR POLYMERIZING OLEFINS | CELANESE HOLDING GMBH (DE) | 2009-07-29 | — | — | EP | disclosed |
| EP-1992630-A1 | Covalently fixed non-metallocenes, method for the production thereof and their use for polymerizing olefins | Celanese Holding GmbH (DE) | 2008-11-19 | — | — | EP | disclosed |
| US-7157398-B2 | Covalently fixed nonmetallocenes, process for preparing them and their use for the polymerization of olefins | CELANESE VENTURES GMBH (DE) | 2007-01-02 | — | — | US | disclosed |
| US-20050148461-A1 | Covalently fixed nonmetallocenes, process for preparing them and their use for the polymerization of olefins | CELANESE VENTURES GMBH (DE) | 2005-07-07 | — | — | US | disclosed |
| US-6872843-B2 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2005-03-29 | — | — | US | disclosed |
| EP-1480987-A1 | COVALENTLY FIXED NON-METALLOCENES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR POLYMERIZING OLEFINS | Celanese Ventures GmbH (DE) | 2004-12-01 | — | — | EP | disclosed |
| US-20040023940-A1 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins | EQUISTAR CHEMICALS, LP | 2004-02-05 | — | — | US | disclosed |
| WO-2003072584-A1 | COVALENTLY FIXED NON-METALLOCENES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR POLYMERIZING OLEFINS | CELANESE VENTURES GMBH (DE) | 2003-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023940-A1 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins | SOAT2, NOTUM, SOAT1 | ERN1 2212/4885LMNA 4296/4885MAPT 1019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.