Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171774 | 0.72 | GRM2 (0.58) | GRM2 | |
| SCHEMBL14865163 | 0.66 | QDPR (0.55) | WNT3A | |
| SCHEMBL22583246 | 0.60 | QDPR (0.50) | — | |
| SCHEMBL29435634 | 0.60 | QDPR (0.50) | — | |
| SCHEMBL12526347 | 0.59 | AOC3 (0.41) | WNT3A | |
| SCHEMBL20753956 | 0.57 | JAK1 (0.52) | WNT3A | |
| SCHEMBL26157119 | 0.56 | SIGMAR1 (0.48) | — | |
| SCHEMBL2922385 | 0.56 | SIGMAR1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL30758819 | 0.55 | DYRK1A (0.35) | WNT3A | |
| SCHEMBL12247662 | 0.55 | DYRK1A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994004-B1 | 1,4-DISUBSTITUTED 3-CYANO-PYRIDONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS | JANSSEN PHARMACEUTICALS INC (US) | 2012-08-01 | — | — | EP | disclosed |