Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26157118 | 0.80 | LMNA (0.42) | SIGMAR1HTR6ALDH1A1TSHRPARP1 | |
| SCHEMBL14601668 | 0.79 | SIGMAR1 (0.60) | SIGMAR1HTR1A | |
| SCHEMBL11938943 | 0.77 | SIGMAR1 (0.65) | SIGMAR1HTR6HTR1A | |
| SCHEMBL8575395 | 0.77 | SIGMAR1 (0.62) | SIGMAR1TDP1PARP1 | |
| SCHEMBL256663 | 0.75 | SIGMAR1 (0.63) | SIGMAR1PARP1HTR1A | |
| SCHEMBL18936739 | 0.74 | SIGMAR1 (0.66) | SIGMAR1HTR6PARP1HTR1A | |
| SCHEMBL18937726 | 0.73 | SIGMAR1 (0.52) | SIGMAR1HTR6PARP1 | |
| SCHEMBL26157120 | 0.73 | HTR6 (0.44) | SIGMAR1HTR6 | |
| SCHEMBL10254250 | 0.72 | SIGMAR1 (0.52) | SIGMAR1HTR6 | |
| SCHEMBL4237702 | 0.72 | SIGMAR1 (0.54) | SIGMAR1ALOX15TDP1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |