Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.30 |
| ▸ | SKP1 | P63208 | 1/20 | 0.30 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13857545 | 0.98 | CA14 (0.51) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL15569713 | 0.80 | CA14 (0.54) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL13055403 | 0.80 | CA14 (0.54) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL15295664 | 0.79 | CA14 (0.45) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL13055399 | 0.78 | CA14 (0.53) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL13055414 | 0.78 | CA14 (0.53) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL13055411 | 0.78 | CA14 (0.53) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL13055400 | 0.77 | CA14 (0.64) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL17532668 | 0.77 | CA14 (0.51) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL12227587 | 0.76 | TDP1 (0.56) | TDP1MEN1GAAKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501478-B2 | Trehalose click polymers for delivery of biologically active molecules | UNIVERSITY OF CINCINNATI (US) | 2013-08-06 | — | — | US | disclosed |
| US-8372966-B2 | Oligonucleotide decoys and methods of use | UNIVERSITY OF CINCINNATI (US) | 2013-02-12 | — | — | US | disclosed |
| US-20120270927-A1 | Polyamides For Nucleic Acid Delivery | UNIVERSITY OF CINCINNATI | 2012-10-25 | — | — | US | disclosed |
| US-8236280-B2 | Polyamides for nucleic acid delivery | UNIVERSITY OF CINCINNATI (US) | 2012-08-07 | — | — | US | disclosed |
| US-8034619-B2 | Polyamides for nucleic acid delivery | UNIVERSITY OF CINCINNATI (US) | 2011-10-11 | — | — | US | disclosed |
| US-20110183417-A1 | POLYAMIDES FOR NUCLEIC ACID DELIVERY | UNIVERSITY OF CINCINNATI | 2011-07-28 | — | — | US | disclosed |
| US-7927873-B2 | Polyamides for nucleic acid delivery | UNIVERSITY OF CINCINNATI (US) | 2011-04-19 | — | — | US | disclosed |
| US-20090124534-A1 | Trehalose Click Polymers for Delivery of Biologically Active Molecules | UNIVERSITY OF CINCINNATI (US) | 2009-05-14 | — | — | US | disclosed |
| US-20090105115-A1 | POLYAMIDES FOR NUCLEIC ACID DELIVERY | UNIVERSITY OF CINCINNATI | 2009-04-23 | — | — | US | disclosed |
| US-20090099108-A1 | OLIGONUCLEOTIDE DECOYS AND METHODS OF USE | UNIVERSITY OF CINCINNATI | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105115-A1 | POLYAMIDES FOR NUCLEIC ACID DELIVERY | TLR3, TLR9, TLR6 | CA14 221/4885TDP1 973/4885MEN1 4001/4885 |
| US-20090124534-A1 | Trehalose Click Polymers for Delivery of Biologically Active Molecules | TREH, TK1, DDOST | CA14 1240/4885TDP1 571/4885MEN1 1648/4885 |
| US-20120270927-A1 | Polyamides For Nucleic Acid Delivery | TLR3, TLR9, DCLRE1A | CA14 383/4885TDP1 803/4885MEN1 3440/4885 |
| US-20090099108-A1 | OLIGONUCLEOTIDE DECOYS AND METHODS OF USE | NFKB2, IKBKB, NFKBIA | CA14 3846/4885TDP1 824/4885MEN1 4766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.