Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.52 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19869036 | 0.84 | ALDH1A1 (0.54) | PPARGPPARAGSTP1GSTM2MAPT | |
| SCHEMBL29740048 | 0.84 | NFKB1 (0.52) | PPARGPPARAGSTP1GSTM2MAPT | |
| SCHEMBL3869417 | 0.83 | PPARG (0.74) | PPARGPPARAGSTP1GSTM2MAPT | |
| SCHEMBL3319460 | 0.81 | PPARG (0.58) | PPARGPPARAGSTP1GSTM2ITGA4 | |
| SCHEMBL2728823 | 0.81 | PPARG (0.58) | PPARGPPARAGSTP1GSTM2ITGA4 | |
| SCHEMBL19212613 | 0.81 | PPARG (0.58) | PPARGPPARAGSTP1GSTM2ITGA4 | |
| SCHEMBL14552051 | 0.77 | PPARG (0.54) | PPARGPPARAGSTP1GSTM2ITGA4 | |
| SCHEMBL25003377 | 0.77 | CYP1A2 (0.55) | PPARGPPARAGSTP1GSTM2MAPT | |
| SCHEMBL9679571 | 0.77 | CYP1A2 (0.55) | PPARGPPARAGSTP1GSTM2MAPT | |
| SCHEMBL20531111 | 0.77 | CYP1A2 (0.55) | PPARGPPARAGSTP1GSTM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236945-B2 | Process for preparing disulfides and thiosulphinates and compounds prepared | Universite Joseph Fourier (Grenoble1) (FR) | 2012-08-07 | — | — | US | disclosed |
| US-8236945-B2 | Process for preparing disulfides and thiosulphinates and compounds prepared | Universite Joseph Fourier (Grenoble1) (FR) | 2012-08-07 | — | — | US | disclosed |
| US-20100075917-A1 | THIONUCLEOSIDES AND PHARMACEUTICAL APPLICATIONS | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2010-03-25 | — | — | US | disclosed |
| US-20100075917-A1 | THIONUCLEOSIDES AND PHARMACEUTICAL APPLICATIONS | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2010-03-25 | — | — | US | disclosed |
| US-20090264637-A1 | PROCESS FOR PREPARING DISULPHIDES AND THIOSULPHINATES AND COMPOUNDS PREPARED | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2009-10-22 | — | — | US | disclosed |
| US-20090264637-A1 | PROCESS FOR PREPARING DISULPHIDES AND THIOSULPHINATES AND COMPOUNDS PREPARED | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2009-10-22 | — | — | US | disclosed |
| WO-2008059130-A1 | THIONUCLEOSIDES AND PHARMACEUTICAL APPLICATIONS | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2008-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264637-A1 | PROCESS FOR PREPARING DISULPHIDES AND THIOSULPHINATES AND COMPOUNDS PREPARED | TST, STS, MSR1 | PPARG 1621/4885PPARA 3045/4885GSTP1 846/4885 |
| US-20100075917-A1 | THIONUCLEOSIDES AND PHARMACEUTICAL APPLICATIONS | TYMP, PNP, NSUN2 | PPARG 2465/4885PPARA 3105/4885GSTP1 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.