Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Koenoline SCHEMBL29904331 | 0.81 | TUBB4A (0.47) | PARP14ALDH1A1FTOMAPTMEN1 | |
| Koenoline SCHEMBL6052281 | 0.81 | TUBB4A (0.47) | PARP14ALDH1A1FTOMAPTMEN1 | |
| SCHEMBL13697482 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2AGABRP | |
| SCHEMBL27986588 | 0.78 | FTO (0.47) | ALDH1A1FTOMAPTMEN1KMT2A | |
| Mukoeic Acid SCHEMBL29460309 | 0.75 | FTO (0.56) | ALDH1A1FTOMAPTMEN1KMT2A | |
| SCHEMBL27929687 | 0.74 | SLC22A6 (0.44) | PARP14ALDH1A1FTOMAPTMEN1 | |
| Mukonine SCHEMBL17817163 | 0.74 | FTO (0.73) | ALDH1A1FTOMAPTGABRPGABRD | |
| Mukonine SCHEMBL30880285 | 0.74 | FTO (0.73) | ALDH1A1FTOMAPTGABRPGABRD | |
| SCHEMBL15203449 | 0.72 | GABRP (0.46) | PARP14ALDH1A1FTOMAPTMEN1 | |
| SCHEMBL11220480 | 0.72 | MAPT (0.60) | ALDH1A1FTOMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8519154-B2 | Method for treatment of bronchial asthma | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-08-27 | — | — | US | disclosed |
| US-8519154-B2 | Method for treatment of bronchial asthma | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-08-27 | — | — | US | disclosed |
| US-20120202868-A1 | METHOD FOR TREATMENT OF BRONCHIAL ASTHMA | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-08-09 | — | — | US | disclosed |
| US-20120202868-A1 | METHOD FOR TREATMENT OF BRONCHIAL ASTHMA | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202868-A1 | METHOD FOR TREATMENT OF BRONCHIAL ASTHMA | CHRM3, CHRM1, CHRM2 | PARP14 2213/4885ALDH1A1 994/4885FTO 4386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.