Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 3/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555841 | 0.80 | LMNA (0.68) | DEGS1SNCANQO2NPC1RAB9A | |
| SCHEMBL8420639 | 0.79 | DEGS1 (0.75) | DEGS1SNCANQO2NPC1RAB9A | |
| SCHEMBL899585 | 0.79 | DEGS1 (0.75) | DEGS1SNCANQO2NPC1RAB9A | |
| SCHEMBL984302 | 0.79 | ESR1 (0.74) | ESR1ESR2KMT2AKDM4ELMNA | |
| SCHEMBL900928 | 0.79 | DEGS1 (0.75) | DEGS1SNCANQO2NPC1RAB9A | |
| SCHEMBL4747814 | 0.77 | TRPV1 (0.61) | DEGS1SNCAESR1ESR2NQO2 | |
| SCHEMBL16610194 | 0.76 | DEGS1 (0.61) | DEGS1SNCANQO2NPC1RAB9A | |
| SCHEMBL28034393 | 0.76 | DEGS1 (0.58) | DEGS1SNCANQO2NPC1RAB9A | |
| SCHEMBL11138237 | 0.75 | ESR1 (0.63) | DEGS1SNCAESR1ESR2BDKRB2 | |
| SCHEMBL11676225 | 0.74 | MEN1 (0.77) | DEGS1SNCANQO2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799663-B1 | Modulators of HCV replication | ANGELETTI P IST RICHERCHE BIO (IT) | 2012-08-01 | — | — | EP | disclosed |