Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 3/20 | 0.58 |
| ▸ | SNCA | P37840 | 2/20 | 0.58 |
| ▸ | NQO2 | P16083 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420639 | 0.85 | DEGS1 (0.75) | DEGS1SNCANQO2POLBKDM4E | |
| SCHEMBL899585 | 0.85 | DEGS1 (0.75) | DEGS1SNCANQO2POLBKDM4E | |
| SCHEMBL900928 | 0.85 | DEGS1 (0.75) | DEGS1SNCANQO2POLBKDM4E | |
| SCHEMBL6555841 | 0.83 | LMNA (0.68) | DEGS1SNCANQO2POLBKDM4E | |
| SCHEMBL4491689 | 0.80 | PTPN1 (0.76) | DEGS1SNCANQO2POLBKMT2A | |
| SCHEMBL2415708 | 0.80 | PTPN1 (0.76) | DEGS1SNCANQO2POLBKMT2A | |
| SCHEMBL8770541 | 0.80 | DEGS1 (0.68) | DEGS1SNCANQO2POLBKDM4E | |
| SCHEMBL20284045 | 0.80 | DEGS1 (0.86) | DEGS1SNCANQO2POLBKDM4E | |
| SCHEMBL11688443 | 0.78 | DEGS1 (0.83) | DEGS1SNCANQO2POLBKDM4E | |
| SCHEMBL2064051 | 0.77 | TRPV1 (0.73) | DEGS1SNCANQO2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085433-B | Substituted amide phenol compound and preparation method thereof, pharmaceutical composition and purposes | 中国科学院上海药物研究所 | 2019-06-25 | — | — | CN | disclosed |
| CN-105085433-A | Substituted-amide phenolic compound, preparation method, pharmaceutical composition and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-11-25 | — | — | CN | disclosed |