SCHEMBL11961395

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3246805	0.88	DAO (0.44)	HDAC4HDAC1HDAC6HDAC3HDAC7
	SCHEMBL3252630	0.88	HDAC3 (0.45)	NPSR1PPARGNCOA2LMNAHDAC4
	SCHEMBL11361990	0.79	LMNA (0.38)	NPSR1PPARGNCOA2LMNANCOA1
	SCHEMBL19775385	0.77	NPC1 (0.33)	HPGDALDH1A1HSD17B10MAPTTP53
	SCHEMBL3246810	0.77	HPGD (0.45)	NPSR1LMNAHDAC4HDAC1HDAC6
	SCHEMBL20082312	0.76	KDM4E (0.43)	HDAC4HDAC1HDAC6HDAC3HDAC7
	SCHEMBL1235256	0.72	LMNA (0.60)	NPSR1PPARGNCOA2LMNANCOA1
	SCHEMBL6498557	0.71	DAO (0.52)	NPSR1PPARGNCOA2LMNANCOA1
	SCHEMBL7885993	0.70	KDM4E (0.50)	NPSR1PPARGNCOA2LMNANCOA1
	SCHEMBL7886029	0.70	HDAC6 (0.65)	NPSR1PPARGNCOA2LMNANCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.