Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.60 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.60 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498557 | 0.90 | DAO (0.52) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL6477476 | 0.90 | KDM4E (0.58) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL23407055 | 0.89 | NPSR1 (0.50) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL19439636 | 0.89 | LMNA (0.50) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL70027 | 0.88 | NPSR1 (0.67) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL20718437 | 0.86 | NPSR1 (0.47) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL31055049 | 0.86 | KDM4E (0.68) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL71536 | 0.85 | RAB9A (0.66) | PPARGNCOA2NCOA1NCOA3HPGD | |
| SCHEMBL29906340 | 0.84 | RAB9A (0.51) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL23436971 | 0.84 | NPSR1 (0.46) | LMNANPSR1PPARGNCOA2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017167638-A1 | NON-AQUEOUS ELECTROLYTES AND USES THEREOF | SONY CORPORATION (JP) | 2017-10-05 | — | — | WO | disclosed |
| US-20110071113-A1 | Thiazole Derivatives and Use Thereof | MERCK SERONO SA (CH) | 2011-03-24 | — | — | US | disclosed |
| US-7888379-B2 | N-[5-(5-formyl-2-thienyl)-4-methyl-1,3-thiazol-2-yl]acetamide; autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer | MERCK SERONO SA (CH) | 2011-02-15 | — | — | US | disclosed |
| US-20080200463-A1 | Thiazole Derivatives and Use Thereof | LABORATOIRES SERONO SA (CH) | 2008-08-21 | — | — | US | disclosed |
| EP-1888573-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125807-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200463-A1 | Thiazole Derivatives and Use Thereof | PDGFRB, PDGFRA, TEC | LMNA 4765/4885NPSR1 1930/4885PPARG 310/4885 |
| US-20110071113-A1 | Thiazole Derivatives and Use Thereof | PDGFRB, PDGFRA, TEC | LMNA 4765/4885NPSR1 1930/4885PPARG 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.