Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 15/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ATXN2 | Q99700 | 9/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11967651 | 0.96 | ENPP2 (0.35) | ENPP2KCNH2ATXN2TMEM97SIGMAR1 | |
| SCHEMBL3047218 | 0.88 | ENPP2 (0.47) | ENPP2KCNH2ATXN2 | |
| SCHEMBL17888827 | 0.86 | ENPP2 (0.40) | ENPP2KCNH2ATXN2SIGMAR1 | |
| SCHEMBL3047207 | 0.84 | ENPP2 (0.47) | ENPP2KCNH2ATXN2 | |
| SCHEMBL1671516 | 0.82 | ENPP2 (0.35) | ENPP2ATXN2SIGMAR1 | |
| SCHEMBL104877 | 0.81 | ENPP2 (0.55) | ENPP2KCNH2ATXN2 | |
| SCHEMBL170045 | 0.81 | ENPP2 (0.46) | ENPP2KCNH2ATXN2 | |
| SCHEMBL1670737 | 0.79 | MGLL (0.34) | — | |
| SCHEMBL1672869 | 0.79 | ENPP2 (0.38) | ENPP2ATXN2 | |
| SCHEMBL1670653 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193118-B1 | PIPERIDINE AND PIPERAZINE DERIVATIVES FOR TREATING TUMOURS | MERCK PATENT GMBH (DE) | 2012-08-22 | — | — | EP | disclosed |