Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | NPC1 | O15118 | 4/20 | 0.77 |
| ▸ | RAB9A | P51151 | 4/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.77 |
| ▸ | PKM | P14618 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.58 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.58 |
| ▸ | KRAS | P01116 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.55 |
| ▸ | P4HB | P07237 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11973091 | 1.00 | MAPT (0.77) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL12257967 | 0.92 | MAPT (0.90) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL4400320 | 0.87 | MAPT (1.00) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL977480 | 0.87 | MAPT (1.00) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL1320225 | 0.86 | KDM4E (0.74) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL1320227 | 0.86 | KDM4E (0.74) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL1604280 | 0.86 | MAPT (0.79) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL31436352 | 0.86 | MAPT (0.79) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL1929871 | 0.84 | PKM (0.82) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL6793176 | 0.84 | RAB9A (0.77) | MAPTNPC1RAB9AKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2626346-B1 | BENZO[K]FLUORANTHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT CONTAINING SAME | IDEMITSU KOSAN CO (JP) | 2018-01-10 | — | — | EP | disclosed |
| CN-104258908-B | A kind of preparation method of dual different rare-earth fluorescent probe compound | 中国工程物理研究院化工材料研究所 | 2016-08-17 | — | — | CN | disclosed |
| US-9273002-B2 | Benzo[k]fluoranthene derivative and organic electroluminescence device containing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2016-03-01 | — | — | US | disclosed |
| EP-2626346-A1 | BENZO[K]FLUORANTHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT CONTAINING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2013-08-14 | — | — | EP | disclosed |
| US-20120211743-A1 | BENZO[k]FLUORANTHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120211743-A1 | BENZO[k]FLUORANTHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME | KCNJ2, KCNE1, KCNK2 | MAPT 2759/4885NPC1 3587/4885RAB9A 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.