Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 4/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3035762 | 0.84 | LCK (0.44) | MAPTPKMLCKTAS1R3TAS1R1 | |
| SCHEMBL11987619 | 0.80 | PKM (0.43) | MAPTPKMLCKHDAC1S1PR4 | |
| SCHEMBL10401801 | 0.78 | S1PR4 (0.60) | MAPTPKMLCKS1PR4NPC1 | |
| SCHEMBL11977445 | 0.77 | CA1 (0.46) | MAPTPKMLCKS1PR4TDP1 | |
| SCHEMBL4975567 | 0.77 | MAPT (0.47) | MAPTPKMLCKHDAC1NPC1 | |
| SCHEMBL16318420 | 0.76 | TP53 (0.65) | MAPTPKMHDAC1NPC1RAB9A | |
| SCHEMBL421089 | 0.74 | PKM (0.59) | MAPTPKMLCKNPC1ALDH1A1 | |
| SCHEMBL3030068 | 0.74 | MAPT (0.41) | MAPTPKMLCKS1PR4NPC1 | |
| SCHEMBL1250383 | 0.74 | RAB9A (0.63) | MAPTPKMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2945096 | 0.73 | HDAC6 (0.69) | HDAC1HDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236828-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-08-07 | — | — | US | disclosed |
| US-20100216850-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216850-A1 | INSECTICIDAL COMPOUNDS | CHRM1, ACHE, CHRM2 | MAPT 2752/4885PKM 3198/4885LCK 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.