Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15541937 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 | |
| SCHEMBL6669595 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 | |
| SCHEMBL31276635 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 | |
| SCHEMBL1846267 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 | |
| SCHEMBL18383650 | 0.94 | SMN1; SMN2 (0.46) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 | |
| SCHEMBL29020573 | 0.92 | SMN1; SMN2 (0.40) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 | |
| SCHEMBL17338688 | 0.89 | PDE4A (0.44) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 | |
| SCHEMBL6666971 | 0.89 | PDE4A (0.44) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 | |
| SCHEMBL31324735 | 0.89 | PDE4A (0.44) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 | |
| SCHEMBL15528782 | 0.89 | PDE4A (0.44) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501478-B2 | Trehalose click polymers for delivery of biologically active molecules | UNIVERSITY OF CINCINNATI (US) | 2013-08-06 | — | — | US | disclosed |
| US-8372966-B2 | Oligonucleotide decoys and methods of use | UNIVERSITY OF CINCINNATI (US) | 2013-02-12 | — | — | US | disclosed |
| US-8372966-B2 | Oligonucleotide decoys and methods of use | UNIVERSITY OF CINCINNATI (US) | 2013-02-12 | — | — | US | disclosed |
| US-20120270927-A1 | Polyamides For Nucleic Acid Delivery | UNIVERSITY OF CINCINNATI | 2012-10-25 | — | — | US | disclosed |
| US-8236280-B2 | Polyamides for nucleic acid delivery | UNIVERSITY OF CINCINNATI (US) | 2012-08-07 | — | — | US | disclosed |
| US-8034619-B2 | Polyamides for nucleic acid delivery | UNIVERSITY OF CINCINNATI (US) | 2011-10-11 | — | — | US | disclosed |
| US-8034619-B2 | Polyamides for nucleic acid delivery | UNIVERSITY OF CINCINNATI (US) | 2011-10-11 | — | — | US | disclosed |
| US-20110183417-A1 | POLYAMIDES FOR NUCLEIC ACID DELIVERY | UNIVERSITY OF CINCINNATI | 2011-07-28 | — | — | US | disclosed |
| US-7927873-B2 | Polyamides for nucleic acid delivery | UNIVERSITY OF CINCINNATI (US) | 2011-04-19 | — | — | US | disclosed |
| US-7927873-B2 | Polyamides for nucleic acid delivery | UNIVERSITY OF CINCINNATI (US) | 2011-04-19 | — | — | US | disclosed |
| US-20090203131-A1 | Polyamides for nucleic acid delivery | UNIVERSITY OF CINCINNATI (US) | 2009-08-13 | — | — | US | disclosed |
| US-20090124534-A1 | Trehalose Click Polymers for Delivery of Biologically Active Molecules | UNIVERSITY OF CINCINNATI (US) | 2009-05-14 | — | — | US | disclosed |
| US-20090105115-A1 | POLYAMIDES FOR NUCLEIC ACID DELIVERY | UNIVERSITY OF CINCINNATI | 2009-04-23 | — | — | US | disclosed |
| US-20090105115-A1 | POLYAMIDES FOR NUCLEIC ACID DELIVERY | UNIVERSITY OF CINCINNATI | 2009-04-23 | — | — | US | disclosed |
| US-20090099108-A1 | OLIGONUCLEOTIDE DECOYS AND METHODS OF USE | UNIVERSITY OF CINCINNATI | 2009-04-16 | — | — | US | disclosed |
| US-20090099108-A1 | OLIGONUCLEOTIDE DECOYS AND METHODS OF USE | UNIVERSITY OF CINCINNATI | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105115-A1 | POLYAMIDES FOR NUCLEIC ACID DELIVERY | TLR3, TLR9, TLR6 | SMN1; SMN2 1838/4885CA14 221/4885ALDH1A1 3978/4885 |
| US-20090124534-A1 | Trehalose Click Polymers for Delivery of Biologically Active Molecules | TREH, TK1, DDOST | SMN1; SMN2 1855/4885CA14 1240/4885ALDH1A1 3444/4885 |
| US-20120270927-A1 | Polyamides For Nucleic Acid Delivery | TLR3, TLR9, DCLRE1A | SMN1; SMN2 1594/4885CA14 383/4885ALDH1A1 4598/4885 |
| US-20090099108-A1 | OLIGONUCLEOTIDE DECOYS AND METHODS OF USE | NFKB2, IKBKB, NFKBIA | SMN1; SMN2 355/4885CA14 3846/4885ALDH1A1 2564/4885 |
| US-20090203131-A1 | Polyamides for nucleic acid delivery | POLN, CTDSP1, MED12 | SMN1; SMN2 1334/4885CA14 762/4885ALDH1A1 4306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.