Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | PAM | P19021 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10938525 | 0.98 | CES1 (0.56) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL7103949 | 0.87 | LMNA (0.64) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL22263578 | 0.82 | ALOX5 (0.61) | HDAC6LMNAPTGS1 | |
| SCHEMBL27263026 | 0.81 | CES1 (0.58) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL15309802 | 0.80 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL10403039 | 0.79 | CES1 (0.56) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL13017383 | 0.79 | CES1 (0.56) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL669706 | 0.79 | CES1 (0.56) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL27959315 | 0.79 | CES1 (0.56) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL13727493 | 0.79 | CA2 (0.58) | AKR1B1MEN1KMT2AFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 885 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250114282-A1 | Dental materials and methods of making and using thereof | Huang, Chong (US) | 2025-04-10 | — | — | US | claimed |
| US-20240423878-A2 | SELF-ADHESIVE FISSURE SEALANT | KULZER GMBH (DE) | 2024-12-26 | — | — | US | claimed |
| US-20240216229-A1 | SELF-ADHESIVE FISSURE SEALANT | KULZER GMBH (DE) | 2024-07-04 | — | — | US | claimed |
| EP-4391827-A1 | METHOD OF MITIGATING OFF-ODORS | Givaudan SA (CH) | 2024-07-03 | — | — | EP | claimed |
| US-20240197577-A1 | SELF-ADHESIVE DENTAL MATERIAL | KULZER GMBH (DE) | 2024-06-20 | — | — | US | claimed |
| WO-2024110805-A1 | CURABLE COMPOSITION FOR USE IN A PROCESS OF TREATING A DENTAL SITUATION IN THE MOUTH OF A PATIENT | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-05-30 | — | — | WO | claimed |
| US-20240052079-A1 | ANTIBACTERIAL ESTER-FREE MONOMERS FOR DENTAL ADHESIVES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-02-15 | — | — | US | claimed |
| EP-4312945-A1 | SELF-ADHESIVE DENTAL MATERIAL | Kulzer GmbH (DE) | 2024-02-07 | — | — | EP | claimed |
| EP-4312947-A1 | SELF-ADHESIVE FISSURE SEALANT | Kulzer GmbH (DE) | 2024-02-07 | — | — | EP | claimed |
| US-20230383093-A1 | COMPOSITION AND METHOD FOR MICROBIAL CONTROL FOR USE WITH POLYMERS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2023-11-30 | — | — | US | claimed |
| EP-1716159-A2 | CYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS | General Electronic Company (US) | 2006-11-02 | — | — | EP | claimed |
| EP-1697386-A1 | ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES | General Electric Company A Corporation of the State of New York (US) | 2006-09-06 | — | — | EP | claimed |
| US-20050282102-A1 | Kit for use by dental professionals | CMS-DENTAL APS (DK) | 2005-12-22 | — | — | US | claimed |
| WO-2005066187-A1 | ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES | GENERAL ELECTRIC COMPANY (US) | 2005-07-21 | — | — | WO | claimed |
| WO-2005066186-A2 | CYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS | GENERAL ELECTRIC COMPANY (US) | 2005-07-21 | — | — | WO | claimed |
| WO-2003072793-A2 | METHOD FOR PRODUCING ALCOHOLS FROM SUBSTRATES BY USING OXIDE REDUCTASES, TWO-PHASE SYSTEM COMPRISING AN AQUEOUS PHASE AND AN ORGANIC PHASE AND DEVICE FOR CARRYING OUT SAID METHOD | Forschungszentrum Jülich GmbH (DE) | 2003-09-04 | — | — | WO | claimed |
| EP-0985333-A1 | NEW PROCESS FOR MODIFICATION OF SURFACES | Cuptronic AB (SE) | 2000-03-15 | — | — | EP | claimed |
| WO-1998034446-A1 | NEW PROCESS FOR MODIFICATION OF SURFACES | CUPTRONIC AB (SE) | 1998-08-06 | — | — | WO | claimed |
| US-5783621-A | Method of decreasing bleed fom organic-based formulations and anti-bleed compositions | JOHNSON MATTHEY, INC. (US) | 1998-07-21 | — | — | US | claimed |
| EP-0382209-A2 | Photocurable composition | NIPPON PAINT CO., LTD. (JP) | 1990-08-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240197577-A1 | SELF-ADHESIVE DENTAL MATERIAL | CAD, MTHFD2, MAT2B | CES1 4093/4885CES2 4175/4885AKR1B1 2363/4885 |
| US-20240052079-A1 | ANTIBACTERIAL ESTER-FREE MONOMERS FOR DENTAL ADHESIVES | CDH1, ICAM1, CAD | CES1 1210/4885CES2 310/4885AKR1B1 2061/4885 |
| US-20240423878-A2 | SELF-ADHESIVE FISSURE SEALANT | ESD, GFER, FUS | CES1 4554/4885CES2 4653/4885AKR1B1 1917/4885 |
| US-20240216229-A1 | SELF-ADHESIVE FISSURE SEALANT | ESD, GFER, FUS | CES1 4554/4885CES2 4653/4885AKR1B1 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.