Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | MGLL | Q99685 | 1/20 | 0.63 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119461 | 0.86 | POLB (0.72) | ALDH1A1POLBMAPTLMNAGAA | |
| SCHEMBL23648938 | 0.81 | ALDH1A1 (0.59) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL7109149 | 0.81 | ALDH1A1 (1.00) | ALDH1A1POLBPRMT1TAAR1HSD17B10 | |
| SCHEMBL12059144 | 0.81 | PRMT1 (0.69) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL3850206 | 0.80 | POLB (0.72) | ALDH1A1POLBMAPTLMNAPRMT1 | |
| SCHEMBL10460747 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL412302 | 0.80 | ALDH1A1 (0.79) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL29123938 | 0.80 | ALDH1A1 (0.70) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL11108949 | 0.80 | AKR1C3 (0.72) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL2916059 | 0.79 | PRMT1 (0.71) | ALDH1A1POLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102427810-A | Sulfamoylbenzoic acid derivatives as TRPM8 antagonists | RAQUALIA PHARMA INC | 2012-04-25 | — | — | CN | disclosed |
| US-20120094964-A1 | SULFAMOYL BENZOIC ACID DERIVATIVES AS TRPM8 ANTAGONISTS | RAQUALIA PHARMA INC. (JP) | 2012-04-19 | — | — | US | disclosed |
| EP-2424517-A1 | SULFAMOYL BENZOIC ACID DERIVATIVES AS TRPM8 ANTAGONISTS | RaQualia Pharma Inc (JP) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010125831-A1 | SULFAMOYL BENZOIC ACID DERIVATIVES AS TRPM8 ANTAGONISTS | RAQUALIA PHARMA INC. (JP) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094964-A1 | SULFAMOYL BENZOIC ACID DERIVATIVES AS TRPM8 ANTAGONISTS | TRPM8, TRPM5, TRPM6 | ALDH1A1 1996/4885POLB 4630/4885MAPT 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.