SCHEMBL11986166

SCHEMBL11986166

C=CC(=O)OCOc1ccc(C(=O)Oc2ccc3c(c2)C(C)(C)c2cc(OC(=O)c4ccc(OCOC(=O)C=C)cc4)ccc2-3)cc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.36
THRB P10828 2/20 0.36
KMT2A Q03164 5/20 0.36
GBA1 P04062 2/20 0.36
RARA P10276 2/20 0.34
RARB P10826 2/20 0.34
MAPT P10636 3/20 0.34
CCNC P24863 1/20 0.34
CDK8 P49336 1/20 0.34
CYP3A4 P08684 1/20 0.34
PDGFRB P09619 1/20 0.33
PDGFRA P16234 1/20 0.33
MEN1 O00255 1/20 0.33
PRSS1 P07477 1/20 0.33
ACR P10323 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13664616 0.98 HIF1A (0.35) HIF1ATHRBKMT2AGBA1RARA
SCHEMBL15480713 0.95 THRB (0.45) HIF1ATHRBKMT2AGBA1RARA
SCHEMBL13226631 0.92 HIF1A (0.38) HIF1ATHRBKMT2AGBA1MAPT
SCHEMBL11986077 0.92 RARA (0.37) HIF1ATHRBKMT2AGBA1RARA
SCHEMBL11986111 0.90 RARA (0.36) HIF1ATHRBKMT2AGBA1RARA
SCHEMBL14185456 0.89 KMT2A (0.36) HIF1ATHRBKMT2AGBA1RARA
SCHEMBL17716770 0.88 HTT (0.42) THRBKMT2AMAPTCYP3A4MEN1
SCHEMBL13806826 0.87 KMT2A (0.36) HIF1AKMT2AGBA1RARARARB
SCHEMBL12769578 0.87 RARA (0.33) THRBKMT2ARARARARBMAPT
SCHEMBL11986083 0.87 SERPINE1 (0.37) HIF1AKMT2ARARARARBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9541690-B2 Film using polymerizable liquid crystal composition containing peeling preventive agent JNC CORPORATION (JP) 2017-01-10 US disclosed
US-9505980-B2 Polymerizable liquid crystal composition and optically anisotropic substance having twist alignment JNC CORPORATION (JP) 2016-11-29 US disclosed
US-9399736-B2 Optically anisotropic substance and liquid crystal display JNC CORPORATION (JP) 2016-07-26 US disclosed
US-9315728-B2 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film JNC CORPORATION (JP) 2016-04-19 US disclosed
US-20160011349-A1 INFRARED REFLECTING FILM AND LAMINATED FILM JNC PETROCHEMICAL CORPORATION (JP) 2016-01-14 US disclosed
US-20150361345-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2015-12-17 US disclosed
US-9080100-B2 Polymerizable liquid crystal composition JNC CORPORATION (JP) 2015-07-14 US disclosed
US-20150177567-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT HAVING THEREOF CHI MEI CORPORATION (TW) 2015-06-25 US disclosed
US-20150146156-A1 OPTICALLY ANISOTROPIC SUBSTANCE AND LIQUID CRYSTAL DISPLAY JNC CORPORATION (JP) 2015-05-28 US disclosed
US-20150108401-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC SUBSTANCE HAVING TWIST ALIGNMENT JNC CORPORATION (JP) 2015-04-23 US disclosed
US-20100143612-A1 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film CHISSO CORPORATION 2010-06-10 US disclosed
US-20100096591-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND POLYMER CHISSO CORPORATION 2010-04-22 US disclosed
US-20100051866-A1 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC PETROCHEMICAL CORPORATION (JP) 2010-03-04 US disclosed
US-7488519-B2 Polymerizable liquid crystal composition CHISSO CORPORATION (JP) 2009-02-10 US disclosed
US-7476423-B2 Polymerizable liquid crystal composition CHISSO CORPORATION (JP) 2009-01-13 US disclosed
US-20080241431-A1 Polymerizable liquid crystal composition CHISSO CORPORATION 2008-10-02 US disclosed
US-7393569-B2 Hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyl acrylates); hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyloxetanes; stabilizes polymerizable liquid crystal compositions for a long time and controls the alignment of liquid crystal molecules CHISSO CORPORATION (JP) 2008-07-01 US disclosed
US-20080152844-A1 Polymerizable liquid crystal composition JNC PETROCHEMICAL CORPORATION (JP) 2008-06-26 US disclosed
US-7378135-B2 Polymerizable liquid crystal composition and optically anisotropic thin film CHISSO CORPORATION (JP) 2008-05-27 US disclosed
US-20080014374-A1 Polymerizable liquid crystal composition JNC PETROCHEMICAL CORPORATION (JP) 2008-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100096591-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND POLYMER PKN1, ZYX, OXER1 HIF1A 2131/4885THRB 3732/4885KMT2A 1370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.