Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | ACR | P10323 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11986166 | 0.98 | HIF1A (0.36) | HIF1ATHRBKMT2AGBA1RARA | |
| SCHEMBL15480713 | 0.93 | THRB (0.45) | HIF1ATHRBKMT2AGBA1RARA | |
| SCHEMBL13226631 | 0.90 | HIF1A (0.38) | HIF1ATHRBKMT2AGBA1MAPT | |
| SCHEMBL11986077 | 0.90 | RARA (0.37) | HIF1ATHRBKMT2AGBA1RARA | |
| SCHEMBL11986111 | 0.88 | RARA (0.36) | HIF1ATHRBKMT2AGBA1RARA | |
| SCHEMBL12769578 | 0.87 | RARA (0.33) | THRBKMT2ARARARARBMAPT | |
| SCHEMBL14185456 | 0.87 | KMT2A (0.36) | HIF1ATHRBKMT2AGBA1RARA | |
| SCHEMBL17716770 | 0.86 | HTT (0.42) | THRBKMT2AMAPTCYP3A4TDP1 | |
| SCHEMBL13806826 | 0.85 | KMT2A (0.36) | HIF1AKMT2AGBA1RARARARB | |
| SCHEMBL11986083 | 0.85 | SERPINE1 (0.37) | HIF1AKMT2ARARARARBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7597945-B2 | Optical compensation film; mixture of three (meth)acrylate monomers: e.g. 2,7-bis(acryloyloxyhexyloxy-1,4-phenylenecarbonyloxy)fluorene, a bis 2-fluoroacrylate monomer, and a cyanobiphenyloxyalkanol ester of (meth)acrylic acid; hardness, heat resistance, weatherability, colorless, LC physical properties | CHISSO CORPORATION (JP) | 2009-10-06 | — | — | US | disclosed |