Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779804 | 0.80 | KDM4E (0.38) | TDP1ALDH1A1KDM4E | |
| SCHEMBL11986273 | 0.79 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL13802153 | 0.79 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL10973567 | 0.77 | LMNA (0.59) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11986268 | 0.77 | MTNR1A (0.44) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11986275 | 0.77 | MTNR1A (0.44) | CA1CA2CA7CA9CA12 | |
| SCHEMBL27891586 | 0.75 | CA12 (0.42) | CA1CA2CA7CA9CA12 | |
| SCHEMBL29279433 | 0.74 | CA1 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3264542 | 0.74 | CA1 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1713002 | 0.73 | CA1 (0.58) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247234-B2 | Isotopically labeled compositions and method | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2012-08-21 | — | — | US | disclosed |
| US-20110269985-A1 | ISOTOPICALLY LABELED COMPOSITIONS AND METHOD | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2011-11-03 | — | — | US | disclosed |
| US-7977102-B2 | Isotopically labeled compositions and method | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2011-07-12 | — | — | US | disclosed |
| US-20080311666-A1 | Isotopically labeled compositions and method | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269985-A1 | ISOTOPICALLY LABELED COMPOSITIONS AND METHOD | SRMS, NES, RPS27A | CA1 2822/4885CA2 4314/4885CA7 3214/4885 |
| US-20080311666-A1 | Isotopically labeled compositions and method | SRMS, NES, RPS27A | CA1 2822/4885CA2 4314/4885CA7 3214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.