Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11987833 | 1.00 | CYP11B1 (0.44) | CYP11B1CYP11B2MKNK1MKNK2NR3C1 | |
| SCHEMBL11987828 | 0.95 | L3MBTL1 (0.49) | CYP11B1CYP11B2MKNK1MKNK2NR3C1 | |
| SCHEMBL11981064 | 0.92 | L3MBTL1 (0.53) | CYP11B1CYP11B2MKNK1MKNK2NR3C1 | |
| SCHEMBL11987859 | 0.92 | MAPK10 (0.41) | CYP11B1CYP11B2MKNK1MKNK2NR3C1 | |
| SCHEMBL17952899 | 0.91 | CYP11B2 (0.42) | CYP11B1CYP11B2MKNK1MKNK2NR3C1 | |
| SCHEMBL17952852 | 0.90 | CHRNB4 (0.46) | CYP11B1CYP11B2MKNK1MKNK2NR3C1 | |
| SCHEMBL10015292 | 0.90 | KDM4E (0.44) | CYP11B1CYP11B2MKNK1MKNK2NR3C1 | |
| SCHEMBL11987839 | 0.90 | L3MBTL1 (0.47) | CYP11B1CYP11B2MKNK1MKNK2NR3C1 | |
| SCHEMBL10015296 | 0.90 | KDM4E (0.44) | CYP11B1CYP11B2MKNK1MKNK2NR3C1 | |
| SCHEMBL12342483 | 0.88 | ATM (0.47) | NR3C1ATMKDM4EL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247771-B1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |