Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2150274 | 0.81 | LMNA (0.43) | HTTNPC1RAB9APOLBMAPT | |
| SCHEMBL2150511 | 0.80 | VCP (0.38) | L3MBTL1HTTNPC1RAB9AMAPT | |
| SCHEMBL24516624 | 0.80 | DDB1 (0.42) | L3MBTL1TACR1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL12286449 | 0.79 | CYP2C9 (0.38) | L3MBTL1HTTNPC1RAB9ATACR1 | |
| SCHEMBL11988930 | 0.78 | TACR1 (0.39) | L3MBTL1HTTNPC1RAB9ATACR1 | |
| SCHEMBL11988843 | 0.75 | CHRM3 (0.36) | L3MBTL1TACR1POLBMAPTCHRM3 | |
| SCHEMBL31721353 | 0.75 | ALDH1A1 (0.39) | L3MBTL1HTTNPC1RAB9ATACR1 | |
| SCHEMBL416619 | 0.73 | TACR1 (0.42) | L3MBTL1NPC1RAB9ATACR1MAPT | |
| SCHEMBL17320197 | 0.73 | TACR1 (0.42) | L3MBTL1NPC1RAB9ATACR1POLB | |
| SCHEMBL17611895 | 0.73 | TACR1 (0.44) | L3MBTL1NPC1RAB9ATACR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565184-A1 | THERAPEUTIC AGENT AND PREVENTATIVE AGENT FOR ALZHEIMER'S DISEASE | Toray Industries, Inc. (JP) | 2013-03-06 | — | — | EP | disclosed |
| US-20130041158-A1 | THERAPEUTIC AGENT AND PREVENTATIVE AGENT FOR ALZHEIMER'S DISEASE | TORAY INDUSTRIES, INC. (JP) | 2013-02-14 | — | — | US | disclosed |
| US-20130041157-A1 | THERAPEUTIC AGENT OR PREVENTIVE AGENT FOR URINE COLLECTION DISORDER | TORAY INDUSTRIES, INC. (JP) | 2013-02-14 | — | — | US | disclosed |
| US-8349874-B2 | Cyclohexane derivative and pharmaceutical use thereof | TORAY INDUSTRIES, INC. (JP) | 2013-01-08 | — | — | US | disclosed |
| US-20120270906-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2012-10-25 | — | — | US | disclosed |
| US-8247569-B2 | Cyclohexane derivative and pharmaceutical use thereof | TORAY INDUSTRIES, INC. (JP) | 2012-08-21 | — | — | US | disclosed |
| US-20110201650-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130041157-A1 | THERAPEUTIC AGENT OR PREVENTIVE AGENT FOR URINE COLLECTION DISORDER | UROD, SORD, IDUA | L3MBTL1 3490/4885HTT 795/4885NPC1 765/4885 |
| US-20120270906-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | CNR2, CNR1, TRPV1 | L3MBTL1 4317/4885HTT 734/4885NPC1 417/4885 |
| US-20130041158-A1 | THERAPEUTIC AGENT AND PREVENTATIVE AGENT FOR ALZHEIMER'S DISEASE | APP, PSEN1, PSEN2 | L3MBTL1 3885/4885HTT 48/4885NPC1 116/4885 |
| US-20110201650-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | CNR2, TRPV1, OPRL1 | L3MBTL1 4133/4885HTT 687/4885NPC1 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.