Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 2/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL5679956 | 1.00 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| Phosphoric Acid SCHEMBL1900203 | 0.95 | HDAC4 (0.46) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| Phosphoric Acid SCHEMBL2425254 | 0.90 | MMP3 (0.54) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL454643 | 0.88 | PDE4B (0.54) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| Pyrophosphoric Acid SCHEMBL27561273 | 0.88 | PDE4B (0.44) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| SCHEMBL14353864 | 0.85 | PDE4B (0.50) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| Phosphoric Acid SCHEMBL28725998 | 0.83 | PDE4B (0.47) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| SCHEMBL29001722 | 0.83 | PDE4B (0.58) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| SCHEMBL1754108 | 0.83 | PDE4B (0.52) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| SCHEMBL8644874 | 0.80 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 683 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025103116-A1 | SHRINKAGE-RESISTANT POLYPHENYLENE ETHER COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF | 金发科技股份有限公司 | 2025-05-22 | — | — | WO | claimed |
| CN-119684538-A | Vinyl modified polyphenyl ether/polystyrene alloy resin, composite material thereof and preparation method thereof | 上海函夏科技有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-117624868-B | Anti-shrinkage polyphenyl ether composition, and preparation method and application thereof | 金发科技股份有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-109262624-B | Novel bionic robot | 南京中律信息科技有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-115322552-B | Low-smoke low-heat release polycarbonate material for rail transit interior trim | 南京聚隆科技股份有限公司 | 2024-09-06 | — | — | CN | claimed |
| CN-118580664-A | PC composite material made of recycled continuous fiber reinforced thermoplastic material | 汉达精密电子(昆山)有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-118530576-A | Flame-retardant polycarbonate resin composition for confined space and application thereof | 黄山晖瑞新材料科技有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-118027633-A | Halogen-free flame-retardant PC/ABS composite material with high impact strength and high thermal deformation temperature | 苏州汉扬精密电子有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-117247651-B | High-strength ABS material for keys and preparation method thereof | 东莞市国亨塑胶科技有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117757249-A | Conductive TPU material and preparation method thereof | 美瑞新材料创新中心(山东)有限公司 | 2024-03-26 | — | — | CN | claimed |
| WO-2006023370-A1 | FLAME-RETARDANT POLYPHENYLENE ETHER COMPOSITIONS, AND RELATED ARTICLES | GENERAL ELECTRIC COMPANY (US) | 2006-03-02 | — | — | WO | claimed |
| US-20060041046-A1 | Flame-retardant polyphenylene ether compositions, and related articles | GENERAL ELECTRIC COMPANY | 2006-02-23 | — | — | US | claimed |
| US-20030176543-A1 | HIGH FLOW POLYPHENYLENE ETHER FORMULATIONS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2003-09-18 | — | — | US | claimed |
| EP-0552355-B1 | FLAME-RETARDED, CONDUCTIVE POLYPHENYLENE ETHER-BASED COMPOSITIONS | GEN ELECTRIC (US) | 1997-12-29 | — | — | EP | claimed |
| US-5466733-A | Polyphenylene ethers and fireproofing agents with polystyrene | GENERAL ELECTRIC COMPANY (US) | 1995-11-14 | — | — | US | claimed |
| EP-0645422-A1 | Flame retardant polycarbonate blends | GENERAL ELECTRIC COMPANY (US) | 1995-03-29 | — | — | EP | claimed |
| EP-0395900-B1 | Thermoplastic composition with boron compound | GEN ELECTRIC (US) | 1994-12-14 | — | — | EP | claimed |
| US-5294654-A | Polymer blend with fibers and phosphonate fire retardant compounds | GENERAL ELECTRIC COMPANY (US) | 1994-03-15 | — | — | US | claimed |
| EP-0552355-A1 | FLAME-RETARDED, CONDUCTIVE POLYPHENYLENE ETHER-BASED COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1993-07-28 | — | — | EP | claimed |
| WO-1993004119-A1 | FLAME-RETARDED, CONDUCTIVE POLYPHENYLENE ETHER-BASED COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1993-03-04 | — | — | WO | claimed |