SCHEMBL3472392

SCHEMBL3472392

CCOC(=O)C1(CC)COC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.42
TSHR P16473 2/20 0.41
RECQL P46063 1/20 0.38
ALDH1A1 P00352 4/20 0.37
POLB P06746 2/20 0.37
LMNA P02545 3/20 0.36
MAPT P10636 2/20 0.36
RAB9A P51151 2/20 0.36
KMT2A Q03164 2/20 0.36
HPGD P15428 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALOX15 P16050 2/20 0.34
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
SOAT1 P35610 1/20 0.34
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11996073 0.86 ATM (0.36) ATMTSHRRECQLALDH1A1POLB
SCHEMBL31463769 0.85 TSHR (0.41) ATMTSHRRECQLALDH1A1POLB
SCHEMBL11996078 0.82 ATM (0.34) ATMTSHRRECQLPOLB
SCHEMBL2295307 0.80 ALDH1A1 (0.42) ATMTSHRALDH1A1POLBLMNA
SCHEMBL20564117 0.80 TSHR (0.47) ATMTSHRRECQLALDH1A1POLB
SCHEMBL19216521 0.77 GAA (0.48) ATMTSHRRECQLALDH1A1POLB
SCHEMBL21385301 0.77 ALDH1A1 (0.39) ATMTSHRRECQLALDH1A1POLB
SCHEMBL1538030 0.77 ATM (0.43) ATMTSHRRECQLALDH1A1POLB
SCHEMBL17454 0.77 SMN1; SMN2 (0.40) ATMALDH1A1POLBLMNARAB9A
SCHEMBL2289682 0.77 SMN1; SMN2 (0.44) ATMALDH1A1POLBLMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8378012-B2 Flame retardant composition and hydrolysis-susceptible resin containing same ICL-IP AMERICA INC. (US) 2013-02-19 US disclosed
US-20100044654-A1 Flame Retardant Composition and Hydrolysis-Susceptible Resin Containing Same ICL-IP AMERICA INC. 2010-02-25 US disclosed
EP-1945711-A1 FLAME RETARDANT COMPOSITION AND HYDROLYSIS-SUSCEPTIBLE RESIN CONTAINING SAME Supresta LLC (US) 2008-07-23 EP disclosed
WO-2007056456-A1 FLAME RETARDANT COMPOSITION AND HYDROLYSIS-SUSCEPTIBLE RESIN CONTAINING SAME SUPRESTA LLC (US) 2007-05-18 WO disclosed
US-4342681-A Use of organic silicon compounds in combination with oxetane compounds, dioxanes or tetrahydrofuranes for stabilizing and brightening polycarbonates which are free from phosphites and free from boric acid esters BAYER AKTIENGESELLSCHAFT (DE) 1982-08-03 US disclosed
US-4102859-A PHOSPHOROUS ACID ESTERS WITH OXETANE COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1978-07-25 US disclosed