SCHEMBL11998181

SCHEMBL11998181

c1ccc(-c2ccc3c(c2)c2cc(-c4ccc5c(c4)c4cc(-c6ccccc6)ccc4n5-c4ccc5c(c4)c4cc(-c6ccccc6)ccc4n5-c4ccccc4)ccc2n3-c2ccc(-c3nnc(-c4ccccc4)o3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 13/20 0.47
▸ RAB9A P51151 13/20 0.47
▸ SMN1; SMN2 Q16637 8/20 0.47
▸ HPGD P15428 5/20 0.46
▸ KDM4E B2RXH2 3/20 0.46
▸ ALDH1A1 P00352 3/20 0.46
▸ GLA P06280 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ ALOX15 P16050 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ NFKB1 P19838 2/20 0.44
▸ NFKB2 Q00653 2/20 0.44
▸ RELA Q04206 2/20 0.44
▸ POLB P06746 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ GAA P10253 1/20 0.42
▸ ATAD2 Q6PL18 1/20 0.41
▸ CA1 P00915 2/20 0.41
▸ CA2 P00918 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11998177 0.96 KDM4E (0.46) NPC1RAB9ASMN1; SMN2HPGDKDM4E
SCHEMBL13230215 0.96 NPC1 (0.52) NPC1RAB9ASMN1; SMN2HPGDKDM4E
SCHEMBL13230206 0.96 NPC1 (0.52) NPC1RAB9ASMN1; SMN2HPGDKDM4E
SCHEMBL12680724 0.96 NPC1 (0.52) NPC1RAB9ASMN1; SMN2HPGDKDM4E
SCHEMBL1924967 0.96 NPC1 (0.52) NPC1RAB9ASMN1; SMN2HPGDKDM4E
SCHEMBL2818977 0.96 NPC1 (0.52) NPC1RAB9ASMN1; SMN2HPGDKDM4E
SCHEMBL15371751 0.95 KDM4E (0.47) NPC1RAB9ASMN1; SMN2HPGDKDM4E
SCHEMBL11998253 0.95 KDM4E (0.47) NPC1RAB9ASMN1; SMN2HPGDKDM4E
SCHEMBL11987978 0.93 KDM4E (0.49) NPC1RAB9ASMN1; SMN2HPGDKDM4E
SCHEMBL11987985 0.93 KDM4E (0.49) NPC1RAB9ASMN1; SMN2HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9543530-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode CHEIL INDUSTRIES, INC. (KR) 2017-01-10 — — US disclosed
US-9543530-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode CHEIL INDUSTRIES, INC. (KR) 2017-01-10 — — US disclosed
US-9478755-B2 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2016-10-25 — — US disclosed
US-9478755-B2 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2016-10-25 — — US disclosed
US-9450193-B2 Compound for organic photoelectric device and organic photoelectric device including the same SAMSUNG SDI CO., LTD. (KR) 2016-09-20 — — US disclosed
US-9450193-B2 Compound for organic photoelectric device and organic photoelectric device including the same SAMSUNG SDI CO., LTD. (KR) 2016-09-20 — — US disclosed
US-20150069368-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-03-12 — — US disclosed
US-20150069368-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-03-12 — — US disclosed
US-20150021585-A1 COMPOSITION FOR ORGANIC LIGHT-EMITTING DIODE, ORGANIC LIGHT-EMITTING LAYER INCLUDING SAME, AND ORGANIC LIGHT-EMITTING DIODE SAMSUNG SDI CO., LTD. (KR) 2015-01-22 — — US disclosed
US-20150021585-A1 COMPOSITION FOR ORGANIC LIGHT-EMITTING DIODE, ORGANIC LIGHT-EMITTING LAYER INCLUDING SAME, AND ORGANIC LIGHT-EMITTING DIODE SAMSUNG SDI CO., LTD. (KR) 2015-01-22 — — US disclosed
US-20140231779-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME KIM HYUNG-SUN (KR) 2014-08-21 — — US disclosed
US-20140231779-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME KIM HYUNG-SUN (KR) 2014-08-21 — — US disclosed
US-20130092913-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO.,LTD. 2013-04-18 — — US disclosed
US-20130092913-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO.,LTD. 2013-04-18 — — US disclosed
US-20130056720-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2013-03-07 — — US disclosed
US-20130056720-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2013-03-07 — — US disclosed
US-20120305900-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2012-12-06 — — US disclosed
US-20120305900-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2012-12-06 — — US disclosed
US-20120211736-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2012-08-23 — — US disclosed
US-20120211736-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2012-08-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120305900-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME PPOX, PIEZO1, CRY1 NPC1 2314/4885RAB9A 1870/4885SMN1; SMN2 4381/4885
US-20130056720-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE AOX1, PPOX, OR51E2 NPC1 3326/4885RAB9A 2558/4885SMN1; SMN2 2391/4885
US-20120211736-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME PPOX, PIEZO1, CRY1 NPC1 2314/4885RAB9A 1870/4885SMN1; SMN2 4381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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