Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PYGL | P06737 | 2/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16471399 | 0.89 | SIRT6 (0.58) | KMT2APKMSIRT6KDM4EMAPT | |
| SCHEMBL30772317 | 0.88 | KMT2A (0.87) | KMT2APKMSIRT6KDM4EMAPT | |
| SCHEMBL27296254 | 0.88 | KMT2A (0.87) | KMT2APKMSIRT6KDM4EMAPT | |
| SCHEMBL27379558 | 0.84 | KMT2A (0.75) | KMT2APKMSIRT6KDM4EMAPT | |
| Benzoylpas SCHEMBL563122 | 0.82 | KMT2A (1.00) | KMT2APKMSIRT6KDM4EMAPT | |
| SCHEMBL7609498 | 0.81 | KMT2A (0.75) | KMT2APKMSIRT6KDM4EMAPT | |
| Benzoylpas SCHEMBL8748163 | 0.81 | KMT2A (0.97) | KMT2APKMSIRT6KDM4EMAPT | |
| Benzoylpas SCHEMBL9770542 | 0.81 | KMT2A (0.97) | KMT2APKMSIRT6KDM4EMAPT | |
| Benzoylpas SCHEMBL29353120 | 0.81 | KMT2A (0.97) | KMT2APKMSIRT6KDM4EMAPT | |
| SCHEMBL3296397 | 0.80 | KMT2A (0.83) | KMT2APKMSIRT6KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029066-B2 | Lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2015-05-12 | — | — | US | disclosed |
| EP-2489512-A1 | A lithographic printing plate precursor | Agfa Graphics N.V. (BE) | 2012-08-22 | — | — | EP | disclosed |