Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 12/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 12/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490992 | 0.94 | PDE5A (0.44) | L3MBTL1KCNA5KCNH2SCD5HCRTR1 | |
| SCHEMBL11971078 | 0.88 | KMT2A (0.47) | L3MBTL1KCNA5KCNH2KMT2A | |
| SCHEMBL5598624 | 0.88 | KMT2A (0.47) | L3MBTL1KCNA5KCNH2KMT2A | |
| SCHEMBL1494428 | 0.74 | ESR1 (0.44) | KCNA5KCNH2KMT2A | |
| SCHEMBL514500 | 0.73 | CA1 (0.58) | L3MBTL1CCR6 | |
| SCHEMBL2886348 | 0.71 | KCNA5 (0.72) | KCNA5KCNH2HCRTR1HCRTR2 | |
| SCHEMBL5598942 | 0.70 | MEN1 (0.43) | KMT2A | |
| SCHEMBL22816556 | 0.69 | L3MBTL1 (0.48) | L3MBTL1PDE5AKMT2A | |
| SCHEMBL1490873 | 0.69 | L3MBTL1 (0.41) | L3MBTL1 | |
| SCHEMBL12676276 | 0.68 | L3MBTL1 (0.53) | L3MBTL1PDE5AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9174960-B2 | Compounds useful against kinetoplastideae parasites | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-11-03 | — | — | US | disclosed |
| US-20120214996-A1 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214996-A1 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | TST, PDXK, TBCB | L3MBTL1 474/4885KCNA5 671/4885KCNH2 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.