Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435642 | 0.86 | L3MBTL1 (0.63) | L3MBTL1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6667251 | 0.84 | L3MBTL1 (0.47) | L3MBTL1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9118493 | 0.84 | KDM4E (0.47) | L3MBTL1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL12002216 | 0.83 | L3MBTL1 (0.65) | L3MBTL1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1754732 | 0.82 | KMT2A (0.71) | L3MBTL1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL21081852 | 0.81 | MAPT (1.00) | L3MBTL1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6201780 | 0.80 | LMNA (0.65) | L3MBTL1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL435667 | 0.79 | ALDH1A1 (0.59) | L3MBTL1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10301489 | 0.79 | L3MBTL1 (0.59) | L3MBTL1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2318407 | 0.78 | KCNA5 (0.47) | L3MBTL1MAPTSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928827-B1 | PYRROLE DERIVATIVES AS THERAPEUTIC COMPOUNDS | MYRIAD GENETICS INC (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2007038684-A2 | PYRROLE DERIVATIVES AS THERAPEUTIC COMPOUNDS | MYRIAD GENETICS, INC. (US) | 2007-04-05 | — | — | WO | disclosed |