Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278773 | 0.95 | CYP1A2 (0.45) | CYP3A4KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL12415075 | 0.95 | KDM4E (0.45) | CYP3A4KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL12922960 | 0.95 | KDM4E (0.45) | CYP3A4KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL13416158 | 0.93 | CYP1A2 (0.43) | CYP3A4KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL278561 | 0.89 | CYP2D6 (0.50) | CYP3A4KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL12922916 | 0.88 | HSD17B1 (0.41) | CYP3A4KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL12415073 | 0.87 | HSD17B1 (0.47) | CYP3A4KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL4055460 | 0.85 | ESR1 (0.41) | CYP3A4KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL18888468 | 0.85 | TP53 (0.40) | CYP3A4KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL25998110 | 0.85 | LMNA (0.45) | CYP3A4KDM4EALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816135-B2 | Trisphenol compound | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-20120220805-A1 | NOVEL TRISPHENOL COMPUND | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220805-A1 | NOVEL TRISPHENOL COMPUND | NCOR1, NCOR2, NCOA1 | CYP3A4 806/4885KDM4E 1565/4885ALDH1A1 987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.