Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29907222 | 1.00 | TRPV4 (0.53) | TRPV4MCL1KMT2AMEN1HSD11B1 | |
| SCHEMBL1501254 | 0.83 | KMT2A (0.42) | TRPV4MCL1KMT2AMEN1HSD11B1 | |
| SCHEMBL12186139 | 0.83 | L3MBTL1 (0.44) | MCL1KMT2AMEN1HSD11B1MCOLN3 | |
| SCHEMBL29627448 | 0.82 | TRPV4 (0.42) | TRPV4KMT2ASMN1; SMN2GAAMCOLN3 | |
| SCHEMBL2426442 | 0.82 | TRPV4 (0.42) | TRPV4KMT2ASMN1; SMN2GAAMCOLN3 | |
| SCHEMBL30678376 | 0.81 | HSD11B1 (0.39) | MCL1KMT2AMEN1HSD11B1SMN1; SMN2 | |
| SCHEMBL30678375 | 0.81 | HSD11B1 (0.39) | MCL1KMT2AMEN1HSD11B1SMN1; SMN2 | |
| SCHEMBL30442459 | 0.81 | SMN1; SMN2 (0.39) | TRPV4MCL1KMT2AMEN1HSD11B1 | |
| SCHEMBL2188372 | 0.81 | CA12 (0.48) | KMT2AMEN1LMNAATMPTGES2 | |
| SCHEMBL2535038 | 0.81 | HSD11B1 (0.39) | MCL1KMT2AMEN1HSD11B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896665-B | Preparation method of 2-chloro-1-methyl-4- (methylsulfonyl) benzene | 湖北工程学院 | 2023-04-07 | — | — | CN | claimed |
| CN-113896665-A | Preparation method of 2-chloro-1-methyl-4- (methylsulfonyl) benzene | 湖北工程学院 | 2022-01-07 | — | — | CN | claimed |
| US-4131619-A | Preparation of 2-chloro-4-toluenesulfonyl chloride | THE DOW CHEMICAL COMPANY (US) | 1978-12-26 | — | — | US | claimed |
| CN-117177975-B | Pyrimido [5,4, D ] pyrimidine compounds, compositions comprising the same and uses thereof | 蒙特利尔大学 | 2026-05-19 | — | — | CN | disclosed |
| US-12479842-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | UNIVERSITE DE MONTREAL (CA) | 2025-11-25 | — | — | US | disclosed |
| US-20250270207-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | UNIVERSITE DE MONTREAL (CA) | 2025-08-28 | — | — | US | disclosed |
| US-20250171463-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. | 2025-05-29 | — | — | US | disclosed |
| US-20250152574-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. | 2025-05-15 | — | — | US | disclosed |
| CN-119731156-A | Emopanamide binding protein inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119118894-A | TRPV4 receptor ligands | 犹他大学研究基金会 | 2024-12-13 | — | — | CN | disclosed |
| US-12139488-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | Université de Montréal (CA) | 2024-11-12 | — | — | US | disclosed |
| WO-1992003423-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |
| US-4721822-A | Process for preparing 2,6-dichlorotoluene | STAUFFER CHEMICAL COMPANY (US) | 1988-01-26 | — | — | US | disclosed |
| US-4163013-A | Diphenylamine-azo-hydrocarbylsulfonylphenyl dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-31 | — | — | US | disclosed |
| US-4131619-A | Preparation of 2-chloro-4-toluenesulfonyl chloride | THE DOW CHEMICAL COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4131619-A | Preparation of 2-chloro-4-toluenesulfonyl chloride | THE DOW CHEMICAL COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4046656-A | Photochlorination process for methyl aromatic compounds | THE DOW CHEMICAL COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
| US-3994873-A | Azo dyestuffs containing sulfonylamino-sulfonyl groups | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-30 | — | — | US | disclosed |
| US-3952065-A | ACTIVATED CARBON-PHOSPHORUS HALIDE OR AZO CATALYST, DECOMPOSITION | VYSKUMNY USTAV AGROCHEMICKEJ TECHNOLOGIE (CS) | 1976-04-20 | — | — | US | disclosed |
| US-3945992-A | DISAZO DYES FOR POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270207-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | BRAF, NRAS, KRAS | TRPV4 3761/4885MCL1 1583/4885KMT2A 2292/4885 |
| US-20250171463-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | EBPL, EBP, CREBBP | TRPV4 4535/4885MCL1 2076/4885KMT2A 3863/4885 |
| US-12139488-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | BRAF, NRAS, KRAS | TRPV4 3761/4885MCL1 1583/4885KMT2A 2292/4885 |
| US-12479842-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | BRAF, NRAS, DPYD | TRPV4 3686/4885MCL1 1681/4885KMT2A 2305/4885 |
| US-20250152574-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | EBPL, EBP, CREBBP | TRPV4 4560/4885MCL1 2257/4885KMT2A 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.